Biomaterials and emerging anticancer therapeutics: engineering the microenvironment

L Gu, DJ Mooney - Nature Reviews Cancer, 2016 - nature.com
The microenvironment is increasingly recognized to have key roles in cancer, and
biomaterials provide a means to engineer microenvironments both in vitro and in vivo to …

Engineering nanoparticles to overcome barriers to immunotherapy

R Toy, K Roy - Bioengineering & translational medicine, 2016 - Wiley Online Library
Advances in immunotherapy have led to the development of a variety of promising
therapeutics, including small molecules, proteins and peptides, monoclonal antibodies, and …

Biomaterials for enhancing anti-cancer immunity

ST Koshy, DJ Mooney - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

Drug delivery with living cells

LAL Fliervoet, E Mastrobattista - Advanced drug delivery reviews, 2016 - Elsevier
The field of drug delivery has grown tremendously in the past few decades by developing a
wide range of advanced drug delivery systems. An interesting category is cell-based drug …

[HTML][HTML] Improving the clinical impact of biomaterials in cancer immunotherapy

JM Gammon, NM Dold, CM Jewell - Oncotarget, 2016 - ncbi.nlm.nih.gov
Immunotherapies for cancer have progressed enormously over the past few decades, and
hold great promise for the future. The successes of these therapies, with some patients …

Interleukin-2 functionalized nanocapsules for T cell-based immunotherapy

SU Frick, MP Domogalla, G Baier, FR Wurm… - Acs Nano, 2016 - ACS Publications
A major demand on immunotherapy is the direct interference with specific immune cells in
vivo. In contrast to antibody-engineered nanoparticles to control dendritic cells function …

Emerging nanotechnologies for cancer immunotherapy

S Shukla, NF Steinmetz - Experimental biology and …, 2016 - journals.sagepub.com
Founded on the growing insight into the complex cancer-immune system interactions,
adjuvant immunotherapies are rapidly emerging and being adapted for the treatment of …