Sepsis occurs when an infection exceeds local tissue containment and induces a series of
dysregulated physiologic responses that result in organ dysfunction. A subset of patients …

Laboratory studies involving repeated exposure to paraquat (PQ) in different animal models
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …

The acute phase of sepsis is characterized by a strong inflammatory reaction. At later stages
in some patients, immunoparalysis may be encountered, which is associated with a poor …

Septic patients with myocardial dysfunction have a 3-fold increase in mortality compared
with patients without cardiovascular impairment, and usually show myocarditis, disruption of …

Introduction The objective of the study is to determine if changes in platelet mitochondrial
function in patients with sepsis are present early after presentation and the association of …

Background The aim was to test the primary hypothesis that in patients suffering from shock,
treatment with N-acetylcysteine (NAC) plus deferoxamine (DFX) decreases the incidence of …

In male mice, sepsis-induced cardiomyopathy develops as a result of dysregulation of
myocardial calcium (Ca 2+) handling, leading to depressed cellular Ca 2+ transients (ΔCa i) …

Background Emerging evidence has linked mitochondrial dysfunction to the pathogenesis of
many renal disorders, including acute kidney injury, sepsis and even chronic kidney …

Oxygen is transported from the atmosphere to the cells by a multistep process involving the
coordinated functioning of the respiratory and cardiovascular systems. The individual steps …

自1983 年国内第l 批儿童重症监护室(pediatric intensive care unit, PICU) 成立至今, 日前PICU
的数量, 规模, 硬件设施及从业人员均发展迅速. 随着PICU 临床实践基地的发展成熟和具有学科 …