Metabolic network modeling of microbial interactions in natural and engineered environmental systems

O Perez-Garcia, G Lear, N Singhal - Frontiers in microbiology, 2016 - frontiersin.org
We review approaches to characterize metabolic interactions within microbial communities
using Stoichiometric Metabolic Network (SMN) models for applications in environmental and …

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

JO Park, SA Rubin, YF Xu, D Amador-Noguez… - Nature chemical …, 2016 - nature.com
In metabolism, available free energy is limited and must be divided across pathway steps to
maintain a negative Δ G throughout. For each reaction, Δ G is log proportional both to a …

[图书][B] Systems biology: a textbook

E Klipp, W Liebermeister, C Wierling, A Kowald - 2016 - books.google.com
This advanced textbook is tailored for an introductory course in Systems Biology and is well-
suited for biologists as well as engineers and computer scientists. It comes with student …

Metabolite damage and metabolite damage control in plants

AD Hanson, CS Henry, O Fiehn… - Annual review of …, 2016 - annualreviews.org
It is increasingly clear that (a) many metabolites undergo spontaneous or enzyme-catalyzed
side reactions in vivo,(b) the damaged metabolites formed by these reactions can be …

Identification of metabolic engineering targets for the enhancement of 1, 4-butanediol production in recombinant E. coli using large-scale kinetic models

S Andreozzi, A Chakrabarti, KC Soh, A Burgard… - Metabolic …, 2016 - Elsevier
Rational metabolic engineering methods are increasingly employed in designing the
commercially viable processes for the production of chemicals relevant to pharmaceutical …

[HTML][HTML] Dynamics of benzoate metabolism in Pseudomonas putida KT2440

S Sudarsan, LM Blank, A Dietrich, O Vielhauer… - Metabolic Engineering …, 2016 - Elsevier
Soil microorganisms mineralize lignin-derived aromatic carbon sources using oxidative
catabolic pathways, such as the β-ketoadipate pathway. Although this aromatic pathway is …

Thermodynamics of the alanine aminotransferase reaction

M Voges, F Schmidt, D Wolff, G Sadowski, C Held - Fluid Phase Equilibria, 2016 - Elsevier
The thermodynamic equilibrium of the aminotransferase reaction from l-alanine and 2-
oxoglutarate to l-glutamate and pyruvate in aqueous solution was investigated in a …

[图书][B] Industrial biotechnology: microorganisms

SY Lee, J Nielsen, G Stephanopoulos - 2016 - books.google.com
The latest volume in the Advanced Biotechnology series provides an overview of the main
production hosts and platform organisms used today as well as promising future cell …

Nicotinamide cofactor ratios in engineered strains of Clostridium thermocellum and Thermoanaerobacterium saccharolyticum

D Beri, DG Olson, EK Holwerda… - FEMS Microbiology …, 2016 - academic.oup.com
Clostridium thermocellum and Thermoanaerobacterium saccharolyticum are bacteria under
investigation for production of biofuels from plant biomass. Thermoanaerobacterium …

Assessment of nitric oxide (NO) redox reactions contribution to nitrous oxide (N2O) formation during nitrification using a multispecies metabolic network model

O Perez‐Garcia, K Chandran… - Biotechnology and …, 2016 - Wiley Online Library
Over the coming decades nitrous oxide (N2O) is expected to become a dominant
greenhouse gas and atmospheric ozone depleting substance. In wastewater treatment …