The healthy human microbiome

J Lloyd-Price, G Abu-Ali, C Huttenhower - Genome medicine, 2016 - Springer
Humans are virtually identical in their genetic makeup, yet the small differences in our DNA
give rise to tremendous phenotypic diversity across the human population. By contrast, the …

The gut‐skin axis in health and disease: a paradigm with therapeutic implications

CA O'Neill, G Monteleone, JT McLaughlin, R Paus - Bioessays, 2016 - Wiley Online Library
As crucial interface organs gut and skin have much in common. Therefore it is unsurprising
that several gut pathologies have skin co‐morbidities. Nevertheless, the reason for this …

[HTML][HTML] Temporal stability of the human skin microbiome

J Oh, AL Byrd, M Park, HH Kong, JA Segre - Cell, 2016 - cell.com
Biogeography and individuality shape the structural and functional composition of the
human skin microbiome. To explore these factors' contribution to skin microbial community …

Antimicrobial peptides and wound healing: biological and therapeutic considerations

ML Mangoni, AM McDermott… - Experimental …, 2016 - Wiley Online Library
Repair of tissue wounds is a fundamental process to re‐establish tissue integrity and regular
function. Importantly, infection is a major factor that hinders wound healing. Multicellular …

Biology and biomarkers for wound healing

LE Lindley, O Stojadinovic, I Pastar… - Plastic and …, 2016 - journals.lww.com
Background: As the population grows older, the incidence and prevalence of conditions that
lead to a predisposition for poor wound healing also increase. Ultimately, this increase in …

Microbiome in healthy skin, update for dermatologists

B Dréno, E Araviiskaia, E Berardesca… - Journal of the …, 2016 - Wiley Online Library
The skin is a complex barrier organ made of a symbiotic relationship between microbial
communities and host tissue via complex signals provided by the innate and the adaptive …

[HTML][HTML] Skin microbiome surveys are strongly influenced by experimental design

JS Meisel, GD Hannigan, AS Tyldsley… - Journal of Investigative …, 2016 - Elsevier
Culture-independent studies to characterize skin microbiota are increasingly common, due
in part to affordable and accessible sequencing and analysis platforms. Compared to culture …

The gut microbiota and metabolic disease: current understanding and future perspectives

T Arora, F Bäckhed - Journal of internal medicine, 2016 - Wiley Online Library
The human gut microbiota has been studied for more than a century. However, of nonculture‐
based techniques exploiting next‐generation sequencing for analysing the microbiota …

Current knowledge on psoriasis and autoimmune diseases

N Ayala-Fontánez, DC Soler… - Psoriasis: Targets and …, 2016 - Taylor & Francis
Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …

The influence of skin microorganisms on cutaneous immunity

Y Belkaid, S Tamoutounour - Nature Reviews Immunology, 2016 - nature.com
The skin is a complex and dynamic ecosystem that is inhabited by many microorganisms.
Recent evidence highlights the profound reliance of the skin immune system on its resident …