Low‐dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice
JD Chandler, C Wongtrakool, SA Banton… - Physiological …, 2016 - Wiley Online Library
Inhalation of cadmium (Cd) is associated with lung diseases, but less is known concerning
pulmonary effects of Cd found in the diet. Cd has a decades‐long half‐life in humans and …
pulmonary effects of Cd found in the diet. Cd has a decades‐long half‐life in humans and …
Pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
Y Xiong, MC Cherrier, JSK Choi, PI Dosa… - US Patent …, 2016 - Google Patents
(57) ABSTRACT Pyrazole derivatives of Formula (Ia) and pharmaceutical compositions
thereof that modulate the activity of the sero tonin 5HT2 receptor. Formula (Ia). Compounds …
thereof that modulate the activity of the sero tonin 5HT2 receptor. Formula (Ia). Compounds …
Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2, 4-difluoro-phenyl)-urea and crystalline forms related thereto
M Carlos, W Dong, M Macias, SM Sato… - US Patent …, 2016 - Google Patents
The present invention is directed to processes and intermedi ates useful for the preparation
of 1-3-(4-bromo-2-methyl 2H-pyrazol-3-yl)-4-methoxy-phenyl-3-(2, 4-difluoro-phe nyl)-urea …
of 1-3-(4-bromo-2-methyl 2H-pyrazol-3-yl)-4-methoxy-phenyl-3-(2, 4-difluoro-phe nyl)-urea …
Allergic sensitization modifies the pulmonary expression of 5-hydroxytryptamine receptors in guinea pigs
There is mounting evidence that 5-hydroxytryptamine (5-HT) plays a role in asthma.
However, scarce information exists about the pulmonary expression of 5-HT receptors and …
However, scarce information exists about the pulmonary expression of 5-HT receptors and …
Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
B Teegarden, D Chapman, J Choi… - US Patent …, 2016 - Google Patents
US9328107B2 - Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin
receptor useful for the treatment of disorders related thereto - Google Patents US9328107B2 …
receptor useful for the treatment of disorders related thereto - Google Patents US9328107B2 …
Caveolin-3: Structural and functional insights into its role in murine airway smooth muscle constriction
M Keshavarz - 2016 - jlupub.ub.uni-giessen.de
Acetylcholine (ACh) and serotonin are bronchoconstrictors clinically relevant in airway
diseases associated with airway hyperreactivity. Their receptors are incorporated in …
diseases associated with airway hyperreactivity. Their receptors are incorporated in …