The impact of comorbidity on cancer and its treatment
Answer questions and earn CME/CNE Comorbidity is common among cancer patients and,
with an aging population, is becoming more so. Comorbidity potentially affects the …
with an aging population, is becoming more so. Comorbidity potentially affects the …
[HTML][HTML] The “efficacy-effectiveness gap”: historical background and current conceptualization
C Nordon, H Karcher, RHH Groenwold, MZ Ankarfeldt… - Value in Health, 2016 - Elsevier
Background The concept of the “efficacy-effectiveness gap”(EEG) has started to challenge
confidence in decisions made for drugs when based on randomized controlled trials alone …
confidence in decisions made for drugs when based on randomized controlled trials alone …
[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies
JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …
to trial participation have been the subject of frequent study, the rate of trial participation has …
Enrollment trends and disparity among patients with lung cancer in national clinical trials, 1990 to 2012
HH Pang, X Wang, TE Stinchcombe… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Under-representation of elderly, women, and racial/ethnic minority patients with
cancer in clinical trials is of national concern. The goal of this study was to characterize …
cancer in clinical trials is of national concern. The goal of this study was to characterize …
[HTML][HTML] Inclusion of elderly patients in oncology clinical trials
Background Physicians need clinical trials assessing benefits and harms of treatments to
avoid under-treatment or over-treatment of elderly patients. The main objectives of this report …
avoid under-treatment or over-treatment of elderly patients. The main objectives of this report …
Disparities in cancer treatment among patients infected with the human immunodeficiency virus
BACKGROUND Patients with cancer who are infected with the human immunodeficiency
virus (HIV) are less likely to receive cancer treatment compared with HIV‐uninfected …
virus (HIV) are less likely to receive cancer treatment compared with HIV‐uninfected …
Impact of geriatric assessment on the management of older adults with head and neck cancer: a pilot study
M Neve, MB Jameson, S Govender… - Journal of geriatric …, 2016 - Elsevier
Objective Assess the utility of the G8 screening tool and CGA for older adults with head and
neck cancer. Methods Patients 65 years or older with a primary malignancy of the head and …
neck cancer. Methods Patients 65 years or older with a primary malignancy of the head and …
Prostate cancer registries: current status and future directions
G Gandaglia, F Bray, MR Cooperberg, RJ Karnes… - European urology, 2016 - Elsevier
Context Disease-specific registries that enroll a considerable number of patients play a
major role in prostate cancer (PCa) research. Objective To evaluate available registries …
major role in prostate cancer (PCa) research. Objective To evaluate available registries …
[HTML][HTML] Chemotherapy in elderly patients with gastric cancer
HS Kim, JH Kim, JW Kim, BC Kim - Journal of Cancer, 2016 - ncbi.nlm.nih.gov
Gastric cancer (GC) is one of the most frequent malignant diseases in the elderly. Systemic
chemotherapy showed an improvement of quality of life and survival benefit compared to …
chemotherapy showed an improvement of quality of life and survival benefit compared to …
Immune checkpoint inhibitors in older adults
R Elias, J Morales, Y Rehman, H Khurshid - Current Oncology Reports, 2016 - Springer
Cancer is primarily a disease of older adults. The treatment of advanced stage tumors
usually involves the use of systemic agents that may be associated with significant risk of …
usually involves the use of systemic agents that may be associated with significant risk of …