Estimating the true global burden of mental illness
We argue that the global burden of mental illness is underestimated and examine the
reasons for under-estimation to identify five main causes: overlap between psychiatric and …
reasons for under-estimation to identify five main causes: overlap between psychiatric and …
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …
patients, but high rates of a partial response or no response, and the delayed onset of the …
Scaling-up treatment of depression and anxiety: a global return on investment analysis
D Chisholm, K Sweeny, P Sheehan… - The Lancet …, 2016 - thelancet.com
Background Depression and anxiety disorders are highly prevalent and disabling disorders,
which result not only in an enormous amount of human misery and lost health, but also lost …
which result not only in an enormous amount of human misery and lost health, but also lost …
The economic costs of mental disorders: Do our societies react appropriately to the burden of mental disorders?
In the EU, about 165 million people are affected each year by mental disorders, mostly
anxiety, mood, and substance use disorders [1, 2]. Overall, more than 50% of the general …
anxiety, mood, and substance use disorders [1, 2]. Overall, more than 50% of the general …
A systematic review of reviews on the prevalence of anxiety disorders in adult populations
Background A fragmented research field exists on the prevalence of anxiety disorders. Here,
we present the results of a systematic review of reviews on this topic. We included the …
we present the results of a systematic review of reviews on this topic. We included the …
Association of hormonal contraception with depression
CW Skovlund, LS Mørch, LV Kessing… - JAMA …, 2016 - jamanetwork.com
Importance Millions of women worldwide use hormonal contraception. Despite the clinical
evidence of an influence of hormonal contraception on some women's mood, associations …
evidence of an influence of hormonal contraception on some women's mood, associations …
How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta‐analytic update of the evidence
We report the current best estimate of the effects of cognitive behavior therapy (CBT) in the
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
Exercise as a treatment for depression: a meta-analysis adjusting for publication bias
The effects of exercise on depression have been a source of contentious debate. Meta-
analyses have demonstrated a range of effect sizes. Both inclusion criteria and …
analyses have demonstrated a range of effect sizes. Both inclusion criteria and …
Cortico-striatal-thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment
The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …
Maltreatment in childhood substantially increases the risk of adult depression and anxiety in prospective cohort studies: systematic review, meta-analysis, and …
BackgroundLiterature supports a strong relationship between childhood maltreatment and
mental illness but most studies reviewed are cross-sectional and/or use recall to assess …
mental illness but most studies reviewed are cross-sectional and/or use recall to assess …