MicroRNA epigenetic signatures in human disease
K Piletič, T Kunej - Archives of toxicology, 2016 - Springer
MicroRNAs (miRNAs) are short non-coding RNAs that act as important regulators of gene
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
Deregulation and therapeutic potential of microRNAs in arthritic diseases
R Vicente, D Noël, YM Pers, F Apparailly… - Nature Reviews …, 2016 - nature.com
Epigenetic abnormalities are part of the pathogenetic alterations involved in the
development of rheumatic disorders. In this context, the main musculoskeletal cell lineages …
development of rheumatic disorders. In this context, the main musculoskeletal cell lineages …
The mechanisms underlying chronic inflammation in rheumatoid arthritis from the perspective of the epigenetic landscape
Y Araki, T Mimura - Journal of immunology research, 2016 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is
characterized by synovial hyperplasia and progressive joint destruction. The activation of RA …
characterized by synovial hyperplasia and progressive joint destruction. The activation of RA …
Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression
C Angiolilli, AM Grabiec, BS Ferguson… - Annals of the …, 2016 - ard.bmj.com
Objectives Epigenetic modifications play an important role in the regulation of gene
transcription and cellular function. Here, we examined if pro-inflammatory factors present in …
transcription and cellular function. Here, we examined if pro-inflammatory factors present in …
Genetic and epigenetic alterations of micro RNA s and implications for human cancers and other diseases
M Tuna, AS Machado, GA Calin - Genes, Chromosomes and …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are a well‐studied group of noncoding RNAs that control gene
expression by interacting mainly with messenger RNA. It is known that miRNAs and their …
expression by interacting mainly with messenger RNA. It is known that miRNAs and their …
MicroRNAs in oral lichen planus and potential miRNA–mRNA pathogenesis with essential cytokines: a review
H Ma, Y Wu, H Yang, J Liu, H Dan, X Zeng… - Oral surgery, oral …, 2016 - Elsevier
Oral lichen planus (OLP) is a potentially premalignant condition with unknown
pathogenesis. Immune and inflammatory factors are thought to play important roles in the …
pathogenesis. Immune and inflammatory factors are thought to play important roles in the …
MicroRNA: a connecting road between apoptosis and cholesterol metabolism
YK Adlakha, N Saini - Tumor Biology, 2016 - Springer
Resistance to apoptosis leads to tumorigenesis and failure of anti-cancer therapy. Recent
studies also highlight abrogated lipid/cholesterol metabolism as one of the root causes of …
studies also highlight abrogated lipid/cholesterol metabolism as one of the root causes of …
[HTML][HTML] AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts
Valosin containing protein (p97) is a chaperone implicated in a large number of biological
processes including endoplasmic reticulum (ER)-associated protein degradation and …
processes including endoplasmic reticulum (ER)-associated protein degradation and …
Synovial fibroblasts: Main players in rheumatoid arthritis
Rheumatoide Arthritis (RA) ist eine Autoimmunerkrankung, die durch eine chronische
Entzündung sowie die Degeneration der Gelenke bis hin zu deren fortwährenden …
Entzündung sowie die Degeneration der Gelenke bis hin zu deren fortwährenden …
Cambios en la expresión de los niveles de microRNAs en suero de pacientes con artritis reumatoide en respuesta al tratamiento con terapia bloqueadora del factor …
MC Castro Villegas - 2016 - helvia.uco.es
La artritis reumatoide (AR) es una enfermedad autoinmune sistémica caracterizada por
sinovitis y destrucción progresiva del cartílago articular y hueso subyacente, junto con …
sinovitis y destrucción progresiva del cartílago articular y hueso subyacente, junto con …