[HTML][HTML] Physiology of intracellular potassium channels: A unifying role as mediators of counterion fluxes?
V Checchetto, E Teardo, L Carraretto, L Leanza… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Plasma membrane potassium channels importantly contribute to maintain ion homeostasis
across the cell membrane. The view is emerging that also those residing in intracellular …
across the cell membrane. The view is emerging that also those residing in intracellular …
[HTML][HTML] Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis
Whether gene repositioning to the nuclear periphery during differentiation adds another
layer of regulation to gene expression remains controversial. Here, we resolve this by …
layer of regulation to gene expression remains controversial. Here, we resolve this by …
[HTML][HTML] Dual function of MG53 in membrane repair and insulin signaling
MG53 is a member of the TRIM-family protein that acts as a key component of the cell
membrane repair machinery. MG53 is also an E3-ligase that ubiquinates insulin receptor …
membrane repair machinery. MG53 is also an E3-ligase that ubiquinates insulin receptor …
[HTML][HTML] Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive …
WA Cabral, M Ishikawa, M Garten, EN Makareeva… - PLoS …, 2016 - journals.plos.org
Recessive osteogenesis imperfecta (OI) is caused by defects in proteins involved in post-
translational interactions with type I collagen. Recently, a novel form of moderately severe OI …
translational interactions with type I collagen. Recently, a novel form of moderately severe OI …
Pore architecture of TRIC channels and insights into their gating mechanism
Intracellular Ca2+ signalling processes are fundamental to muscle contraction,
neurotransmitter release, cell growth and apoptosis,. Release of Ca2+ from the intracellular …
neurotransmitter release, cell growth and apoptosis,. Release of Ca2+ from the intracellular …
[HTML][HTML] Activation of SK2 channels preserves ER Ca2+ homeostasis and protects against ER stress-induced cell death
M Richter, N Vidovic, B Honrath, P Mahavadi… - Cell Death & …, 2016 - nature.com
Alteration of endoplasmic reticulum (ER) Ca 2+ homeostasis leads to excessive cytosolic Ca
2+ accumulation and delayed neuronal cell death in acute and chronic neurodegenerative …
2+ accumulation and delayed neuronal cell death in acute and chronic neurodegenerative …
Mice lacking the intracellular cation channel TRIC-B have compromised collagen production and impaired bone mineralization
C Zhao, A Ichimura, N Qian, T Iida, D Yamazaki… - Science …, 2016 - science.org
The trimeric intracellular cation (TRIC) channels TRIC-A and TRIC-B localize predominantly
to the endoplasmic reticulum (ER) and likely support Ca2+ release from intracellular stores …
to the endoplasmic reticulum (ER) and likely support Ca2+ release from intracellular stores …
[HTML][HTML] Two novel mutations in TMEM38B result in rare autosomal recessive osteogenesis imperfecta
Osteogenesis imperfecta (OI) is a group of clinically and genetically heterogeneous
disorders characterized by decreased bone mass and recurrent bone fractures …
disorders characterized by decreased bone mass and recurrent bone fractures …
[HTML][HTML] Crystal structures of the TRIC trimeric intracellular cation channel orthologues
G Kasuya, M Hiraizumi, AD Maturana, K Kumazaki… - Cell research, 2016 - nature.com
Ca 2+ release from the sarcoplasmic reticulum (SR) and endoplasmic reticulum (ER) is
crucial for muscle contraction, cell growth, apoptosis, learning and memory. The trimeric …
crucial for muscle contraction, cell growth, apoptosis, learning and memory. The trimeric …
[图书][B] OMICS: biomedical perspectives and applications
D Barh, K Blum, MA Madigan - 2016 - books.google.com
A reflection of the explosion of research and development in this field, this book explores
applications of omics in bioinformatics, cancer research and therapy, diabetes research …
applications of omics in bioinformatics, cancer research and therapy, diabetes research …