[HTML][HTML] From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

GB Rogers, DJ Keating, RL Young, ML Wong… - Molecular …, 2016 - nature.com
The human body hosts an enormous abundance and diversity of microbes, which perform a
range of essential and beneficial functions. Our appreciation of the importance of these …

Parent–offspring transaction: Mechanisms and the value of within family designs

JM Jenkins, P McGowan, A Knafo-Noam - Hormones and Behavior, 2016 - Elsevier
This article is part of a Special Issue “Parental Care”. Parenting is best understood as a
transactional process between parents and their offspring. Each responds to cues in the …

Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspring

AE Graf, SW Lallier, G Waidyaratne… - Brain, behavior, and …, 2016 - Elsevier
Maternal obesity induces chronic inflammatory responses that impact the fetus/neonate
during the perinatal period. Inflammation, iron regulation, and myelination are closely …

[HTML][HTML] The role of steroid hormones in the modulation of neuroinflammation by dietary interventions

AR Vasconcelos, JV Cabral-Costa… - Frontiers in …, 2016 - frontiersin.org
Steroid hormones, such as sex hormones and glucocorticoids, have been demonstrated to
play a role in different cellular processes in the central nervous system, ranging from …

Prenatal exposure to maternal obesity alters anxiety and stress coping behaviors in aged mice

G Balsevich, V Baumann, A Uribe, A Chen… - …, 2016 - karger.com
Background: There is growing evidence that maternal obesity and prenatal exposure to a
high-fat diet program fetal development to regulate the physiology and behavior of the …

[HTML][HTML] Exposure to a highly caloric palatable diet during pregestational and gestational periods affects hypothalamic and hippocampal endocannabinoid levels at …

MT Ramírez-López, M Vázquez, L Bindila… - Frontiers in Behavioral …, 2016 - frontiersin.org
Exposure to unbalanced diets during pre-gestational and gestational periods may result in
long-term alterations in metabolism and behavior. The contribution of the endocannabinoid …

[HTML][HTML] Exposure to a highly caloric palatable diet during the perinatal period affects the expression of the endogenous cannabinoid system in the brain, liver and …

MT Ramírez-López, R Arco, J Decara, M Vázquez… - PLoS one, 2016 - journals.plos.org
Recent studies have linked gestational exposure to highly caloric diets with a disrupted
endogenous cannabinoid system (ECS). In the present study, we have extended these …

From genome-wide association study to phenome-wide association study: new paradigms in obesity research

YP Zhang, YY Zhang, DD Duan - Progress in molecular biology and …, 2016 - Elsevier
Obesity is a condition in which excess body fat has accumulated over an extent that
increases the risk of many chronic diseases. The current clinical classification of obesity is …

[HTML][HTML] Maternal high-fat diet influences stroke outcome in adult rat offspring

CC Lin, B Shao, YL Zhou, XT Niu… - Journal of molecular …, 2016 - jme.bioscientifica.com
Diet-induced epigenetic modifications in early life could contribute to later health problem.
However, it remains to be established whether high-fat diet (HFD) consumption during …

The effect of maternal overnutrition on reward and anxiety in offspring

A Sasaki, S Erb, PO McGowan - Parental Obesity: Intergenerational …, 2016 - Springer
Obesity has reached epidemic levels in developed countries. Maternal overnutrition has
been linked to a number of poor health outcomes in offspring, including metabolic …