Once deemed heretical, emerging evidence now supports the notion that the inheritance of
acquired characteristics can occur through ancestral exposures or experiences and that …

Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

Obesity is a heritable disorder, with children of obese fathers at higher risk of developing
obesity. Environmental factors epigenetically influence somatic tissues, but the contribution …

Polycomb group proteins and the related histone modification H3K27me3 can maintain the
silencing of key developmental regulators and provide cellular memory. However, how such …

Epigenetic modifications established during gametogenesis regulate transcription and other
nuclear processes in gametes, but also have influences in the zygote, embryo and postnatal …

Trajectories toward risk or resilience in psychiatric disorders are influenced by acquired and
inherited factors. More recently, evidence from rodent studies suggest that acquired risk …

For a long time, it has been assumed that the only role of sperm at fertilization is to introduce
the male genome into the egg. Recently, ideas have emerged that the epigenetic state of the …

Background During the process of spermatogenesis, male germ cells undergo dramatic
chromatin reorganization, whereby most histones are replaced by protamines, as part of the …

The inheritance of information beyond DNA sequence, known as epigenetic inheritance, has
been implicated in a multitude of biological processes from control of plant flowering time to …

Epidemiology formed the basis of 'the Barker hypothesis', the concept of 'developmental
programming'and today's discipline of the Developmental Origins of Health and Disease …