Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all
microorganisms. With few exceptions, they are chromosomally encoded and present a …

Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …

Background Pseudomonas aeruginosa is not a frequent pathogen in community-acquired
pneumonia (CAP). However, in patients with severe CAP, P aeruginosa can be the etiology …

Multidrug-resistant mutants of Pseudomonas aeruginosa that overproduce the active efflux
system MexEF-OprN (called nfxC mutants) have rarely been characterized in the hospital …

Background Biocides and antibiotics are used to eradicate or prevent the growth of microbial
species on surfaces (occasionally on catheters), or infected sites, either in combination or …

The World Health Organization has identified quinolones, third‐and fourth‐generation
cephalosporins, and macrolides as the most important antibiotics in human medicine. In the …

В коллективной монографии обобщены современные данные по распространенности
в мире, экологии и эпидемиологии патогенных буркхольдерий, их геномной …

The global transcriptional regulator mexT, is a mutational hotspot; the sequence variants
commonly seen to co-exist within the P. aeruginosa population are: drug susceptible (eg …