Colorectal cancer (CRC) results from the progressive accumulation of genetic and
epigenetic alterations that lead to the transformation of normal colonic mucosa to …

Abstract Purpose and Experimental Design: The molecular events in the malignant
progression of colon adenoma after loss of adenomatous polyposis coli (APC) are not fully …

Alterations in the DNA sequences of genes, or mutations, have traditionally been viewed as
the primary factors driving tumor progression, however, epigenetic evidence would suggest …

Colorectal cancer is one of the most common malignancies and the leading cause of cancer-
related death. There are 4 basic colon carcinogenic steps: malignant transformation of …

Napjainkra a vastagbéldaganatok diagnosztikája, terápiája, követése nagy fejlődésen ment
át-sok esetben a nagy áteresztő képességű molekuláris technikáknak, mint például a …

Dynamic alterations in the actin cytoskeleton, under the regulation of the Rho/ROCK
pathway, permit cell motility, cell-to-cell and cell-to-matrix adhesion, and have also been …

[eng] Colorectal cancer is a disease caused by genetic and epigenetic changes. Inactivation
of tumor suppressor genes and activation of oncogenes are key landmarks in tumor …