Pathophysiology of native coronary, vein graft, and in-stent atherosclerosis

K Yahagi, FD Kolodgie, F Otsuka, AV Finn… - Nature Reviews …, 2016 - nature.com
Plaque rupture, usually of a precursor lesion known as a'vulnerable plaque'or'thin-cap
fibroatheroma', is the leading cause of thrombosis. Less-frequent aetiologies of coronary …

[HTML][HTML] High shear stress relates to intraplaque haemorrhage in asymptomatic carotid plaques

A Tuenter, M Selwaness, AA Lorza, JCH Schuurbiers… - Atherosclerosis, 2016 - Elsevier
Background and aims Carotid artery plaques with vulnerable plaque components are
related to a higher risk of cerebrovascular accidents. It is unknown which factors drive …

AMP-activated protein kinase alpha 2 deletion induces VSMC phenotypic switching and reduces features of atherosclerotic plaque stability

Y Ding, M Zhang, W Zhang, Q Lu, Z Cai… - Circulation …, 2016 - Am Heart Assoc
Rationale: AMP-activated protein kinase (AMPK) has been reported to play a protective role
in atherosclerosis. However, whether AMPKα2 controls atherosclerotic plaque stability …

Three-dimensional carotid plaque MR imaging

C Yuan, DL Parker - Neuroimaging Clinics, 2016 - neuroimaging.theclinics.com
Carotid atherosclerosis, especially atherosclerotic plaques at the carotid bifurcation, is a
significant cause of ischemic stroke, a leading cause of death and disability worldwide. A …

Prediction of carotid intraplaque hemorrhage using adventitial calcification and plaque thickness on CTA

LB Eisenmenger, BW Aldred, SE Kim… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Carotid intraplaque hemorrhage is associated with stroke,
plaque thickness, stenosis, ulceration, and adventitial inflammation. Conflicting data exist on …

[HTML][HTML] Carotid plaque fissure: an underestimated source of intraplaque hemorrhage

MJ Daemen, MS Ferguson, FJ Gijsen, DS Hippe… - Atherosclerosis, 2016 - Elsevier
Background and aims Plaque fissuring, a phenomenon morphologically distinct from the
classical rupture of a thinned fibrous cap, has not been well characterized in carotid …

[HTML][HTML] Determinants of carotid atherosclerotic plaque burden in a stroke-free population

M Selwaness, R Hameeteman, R Van't Klooster… - Atherosclerosis, 2016 - Elsevier
Background and aims In a large stroke-free population, we sought to identify cardiovascular
risk factors and carotid plaque components associated with carotid plaque burden, lumen …

High-intensity signal in carotid plaque on routine 3D-TOF-MRA is a risk factor of ischemic stroke

K Yamada, M Kawasaki, S Yoshimura… - Cerebrovascular …, 2016 - karger.com
Background: Carotid atherosclerotic disease is recognized as an important risk factor for
brain ischemic events. However, high-grade stenosis does not always cause ischemic …

Blood pressure is a major modifiable risk factor implicated in pathogenesis of intraplaque hemorrhage: an in vivo magnetic resonance imaging study

J Sun, G Canton, N Balu, DS Hippe, D Xu… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Effective prevention and management strategies of intraplaque hemorrhage
(IPH) remain elusive because of our limited knowledge regarding its contributing factors …

In Vivo Validation of Simultaneous Non-Contrast Angiography and intraPlaque Hemorrhage (SNAP) Magnetic Resonance Angiography: An Intracranial Artery Study

J Wang, M Guan, K Yamada, DS Hippe, WS Kerwin… - PLoS …, 2016 - journals.plos.org
Objectives Simultaneous Non-contrast Angiography and intraPlaque hemorrhage (SNAP)
technique was recently proposed for joint MRA and intraplaque hemorrhage (IPH) imaging …