Abstract Lung metastases occur in 10–20% of patients with colorectal cancer. The biology of
colorectal lung metastases is poorly understood, however lung metastases are more …

Liver and pulmonary metastases (PMs) are relatively common in patients with colorectal
cancer. The majority of metastases are suitable for surgical resection, and the effectiveness …

KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more
frequently than KRAS wild‐type (WT) counterpart. We retrospectively investigated the …

Background The survival benefit of adjuvant chemotherapy after colorectal cancer (CRC)
lung metastasectomy is uncertain. Methods We enrolled 221 CRC patients who underwent …

The development and progression of CRC are regarded as a complicated network and
progressive event including genetic and/or epigenetic alterations. Recent researches …

Introduction While the role of KRAS in the molecular genetics of colorectal cancer has been
studied extensively, its prognostic impact in colorectal liver metastases (CRLM) has only …

AIM: To investigate the impact of RAS and BRAF mutations on the pattern of metastatic
disease and carcinoembryonic antigen (CEA) production. METHODS: In this retrospective …

Introduction: Colorectal liver metastasis (CRLM) is the most frequent indication for liver
resection in many centers. Recent improvements in oncology, surgery, interventional …

Some successes have been achieved in the war on cancer over the past 30 years with
recent efforts on protein kinase inhibitors. Nonetheless, we are still facing challenges due to …

Overall survival (OS) is a statistical term referring to the percentage of a population in a
group who are alive after a defined length of time, usually years. For example, a 5-year OS …