Calcium channels and associated receptors in malignant brain tumor therapy

FB Morrone, MP Gehring, NF Nicoletti - Molecular pharmacology, 2016 - ASPET
Malignant brain tumors are highly lethal and aggressive. Despite recent advances in the
current therapies, which include the combination of surgery and radio/chemotherapy, the …

TRPC channels: prominent candidates of underlying mechanism in neuropsychiatric diseases

C Zeng, F Tian, B Xiao - Molecular neurobiology, 2016 - Springer
Alterations in intracellular Ca 2+ concentration ([Ca 2+] i) play a crucial role in fundamental
cellular events from transcriptional regulation to migration and proliferation. The transient …

Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential

T Xu, Z Fan, W Li, B Dietel, Y Wu, MW Beckmann… - Scientific reports, 2016 - nature.com
Brain tumors are fast proliferating and destructive within the brain microenvironment.
Effective chemotherapeutic strategies are currently lacking which combat this deadly …

[引用][C] 脑胶质瘤侵袭性研究进展

王栋良, 陈谦学 - 医学综述, 2016