Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements
Turnover numbers, also known as k cat values, are fundamental properties of enzymes.
However, k cat data are scarce and measured in vitro, thus may not faithfully represent the in …
However, k cat data are scarce and measured in vitro, thus may not faithfully represent the in …
Stoichiometric representation of gene–protein–reaction associations leverages constraint-based analysis from reaction to gene-level phenotype prediction
Genome-scale metabolic reconstructions are currently available for hundreds of organisms.
Constraint-based modeling enables the analysis of the phenotypic landscape of these …
Constraint-based modeling enables the analysis of the phenotypic landscape of these …
Translation elicits a growth rate‐dependent, genome‐wide, differential protein production in Bacillus subtilis
O Borkowski, A Goelzer, M Schaffer… - Molecular systems …, 2016 - embopress.org
Complex regulatory programs control cell adaptation to environmental changes by setting
condition‐specific proteomes. In balanced growth, bacterial protein abundances depend on …
condition‐specific proteomes. In balanced growth, bacterial protein abundances depend on …
A comparison of the costs and benefits of bacterial gene expression
To study how a bacterium allocates its resources, we compared the costs and benefits of
most (86%) of the proteins in Escherichia coli K-12 during growth in minimal glucose …
most (86%) of the proteins in Escherichia coli K-12 during growth in minimal glucose …
Modelling and optimization of metabolic pathways in bacteria
G Jeanne, S Tebbani, A Goelzer… - … on System Theory …, 2016 - ieeexplore.ieee.org
The rational bacterial strain design is a major challenge in synthetic biology. This paper
deals with the optimization of a bacterial strain for specific processes taking place in a …
deals with the optimization of a bacterial strain for specific processes taking place in a …
Représentation systémique multi-échelle des processus biologiques de la bactérie
VJ Henry, A Ferré, C Froidevaux, A Goelzer… - IC2016-Ingénierie des …, 2016 - hal.science
La production à haut-débit de données biologiques de nature hétérogène nécessite une
exploitation et une intégration particulières de celles-ci. Malgré le développement de …
exploitation et une intégration particulières de celles-ci. Malgré le développement de …
Prédiction de la structure de contrôle de bactéries par optimisation sous incertitude
MA El Faqir - 2016 - theses.hal.science
L'approche de la biologie des systèmes vise à intégrer les méthodologies appliquées dans
la conception et l'analyse des systèmes technologiques complexes, au sein de la biologie …
la conception et l'analyse des systèmes technologiques complexes, au sein de la biologie …
[PDF][PDF] A Comparison of the Costs and Benefits of Bacterial Gene Expression by Morgan N. Price, Kelly M. Wetmore, Adam M. Deutschbauer and Adam P. Arkin; …
MN Price - 2016 - scholar.archive.org
To study how a bacterium allocates its resources, we compared the costs and benefits of
most of the proteins in Escherichia coli K-12 during growth in minimal glucose medium …
most of the proteins in Escherichia coli K-12 during growth in minimal glucose medium …