Genetics of tinnitus: an emerging area for molecular diagnosis and drug development

JA Lopez-Escamez, T Bibas, RFF Cima… - Frontiers in …, 2016 - frontiersin.org
Subjective tinnitus is the perception of sound in the absence of external or bodily-generated
sounds. Chronic tinnitus is a highly prevalent condition affecting over 70 million people in …

Measuring the moment-to-moment variability of tinnitus: the TrackYourTinnitus smart phone app

W Schlee, RC Pryss, T Probst, J Schobel… - Frontiers in aging …, 2016 - frontiersin.org
Tinnitus, the phantom perception of sound without a corresponding external sound, is a
frequent disorder which causes significant morbidity. So far there is no treatment available …

Emotional states as mediators between tinnitus loudness and tinnitus distress in daily life: Results from the “TrackYourTinnitus” application

T Probst, R Pryss, B Langguth, W Schlee - Scientific reports, 2016 - nature.com
The psychological process how tinnitus loudness leads to tinnitus distress remains unclear.
This cross-sectional study investigated the mediating role of the emotional state “stress …

Increased synchrony and bursting of dorsal cochlear nucleus fusiform cells correlate with tinnitus

C Wu, DT Martel, SE Shore - Journal of Neuroscience, 2016 - Soc Neuroscience
Tinnitus, the perception of phantom sounds, is thought to arise from increased neural
synchrony, which facilitates perceptual binding and creates salient sensory features in the …

Visions on the future of medical devices in spinal cord stimulation: what medical device is needed?

D De Ridder, S Vanneste - Expert review of medical devices, 2016 - Taylor & Francis
Recently burst stimulation and 10 kHz stimulation have been developed as novel stimulation
designs. Both appear to be superior to classical tonic stimulation in the amount of …

Differential tinnitus-related neuroplastic alterations of cortical thickness and surface area

M Meyer, P Neff, F Liem, T Kleinjung, S Weidt… - Hearing Research, 2016 - Elsevier
Structural neuroimaging techniques have been used to identify cortical and subcortical
regions constituting the neuroarchitecture of tinnitus. One recent investigation used voxel …

[HTML][HTML] Development and technical functionality of an Internet-based intervention for tinnitus in the UK

EW Beukes, G Vlaescu, V Manchaiah, DM Baguley… - Internet …, 2016 - Elsevier
Purpose Creative approaches to improve access to evidence-based tinnitus treatments are
required. The purpose of this study was to develop an Internet-based cognitive behavioural …

[HTML][HTML] An investigation of feasibility and safety of bi-modal stimulation for the treatment of tinnitus: an open-label pilot study

C Hamilton, S D'Arcy, BA Pearlmutter… - … : Technology at the …, 2016 - Elsevier
Objectives Tinnitus is the perception of sound in the absence of an external auditory
stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a …

The importance of aging in gray matter changes within tinnitus patients shown in cortical thickness, surface area and volume

HB Yoo, D De Ridder, S Vanneste - Brain topography, 2016 - Springer
Aging and sensorineural hearing loss are known to be involved in the development of
chronic tinnitus. This study explores the structural changes of gray matter using surface base …

Effects of long-term salicylate administration on synaptic ultrastructure and metabolic activity in the rat CNS

B Yi, S Hu, C Zuo, F Jiao, J Lv, D Chen, Y Ma… - Scientific Reports, 2016 - nature.com
Tinnitus is associated with neural hyperactivity in the central nervous system (CNS).
Salicylate is a well-known ototoxic drug, and we induced tinnitus in rats using a model of …