[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …
[HTML][HTML] Microneedles: a new frontier in nanomedicine delivery
This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …
Microneedle patches for vaccination in developing countries
J Arya, MR Prausnitz - Journal of Controlled Release, 2016 - Elsevier
Millions of people die of infectious diseases each year, mostly in developing countries,
which could largely be prevented by the use of vaccines. While immunization rates have …
which could largely be prevented by the use of vaccines. While immunization rates have …
The success of microneedle-mediated vaccine delivery into skin
Microneedles (MNs) are designed to specifically target the outermost, skin barrier layer, the
stratum corneum, creating transient pathways for minimally invasive transcutaneous …
stratum corneum, creating transient pathways for minimally invasive transcutaneous …
Rabies vaccination in dogs using a dissolving microneedle patch
JM Arya, K Dewitt, M Scott-Garrard, YW Chiang… - Journal of Controlled …, 2016 - Elsevier
Because humans get rabies primarily through dog bites, stray dog population control and
mass or mandatory vaccination of domestic dogs and other animals has virtually eliminated …
mass or mandatory vaccination of domestic dogs and other animals has virtually eliminated …
[HTML][HTML] Microneedles with controlled bubble sizes and drug distributions for efficient transdermal drug delivery
Drug loaded dissolving microneedles (DMNs) fabricated with water soluble polymers have
received increasing attentions as a safe and efficient transdermal drug delivery system …
received increasing attentions as a safe and efficient transdermal drug delivery system …
Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy
Maternal and neonatal tetanus claim tens of thousands lives every year in developing
countries, but could be prevented by hygienic practices and improved immunization of …
countries, but could be prevented by hygienic practices and improved immunization of …
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71
Recent large outbreaks of hand-foot-and-mouth disease (HFMD) have seriously affected the
health of young children. Enterovirus 71 (EV71) is the main causative agent of HFMD …
health of young children. Enterovirus 71 (EV71) is the main causative agent of HFMD …
Improving global vaccine accessibility
Highlights•GAVI and its partners provide inexpensive vaccines to low-income
countries.•Various barriers exist to providing global accessibility to vaccines.•Circumventing …
countries.•Various barriers exist to providing global accessibility to vaccines.•Circumventing …
Nanoparticulate mediated transcutaneous immunization: Myth or reality
Transcutaneous immunization (TCI) is a promising route of vaccine delivery through skin
due to many well documented advantages. The main obstacle in TCI is the skin's top dead …
due to many well documented advantages. The main obstacle in TCI is the skin's top dead …