[HTML][HTML] Genetic determinants of polycystic ovary syndrome: progress and future directions

MR Jones, MO Goodarzi - Fertility and sterility, 2016 - Elsevier
The field of the genetics of polycystic ovary syndrome (PCOS) has relatively recently moved
into the era of genome-wide association studies. This has led to the discovery of 16 robust …

Associations of insulin receptor and insulin receptor substrates genetic polymorphisms with polycystic ovary syndrome: A systematic review and meta‐analysis

X Shi, X Xie, Y Jia, S Li - Journal of Obstetrics and Gynaecology …, 2016 - Wiley Online Library
Aim Recently, the roles of insulin receptor (INSR) and insulin receptor substrate (IRS)
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …

Is polycystic ovary syndrome a sexual conflict? A review

L Casarini, M Simoni, G Brigante - Reproductive biomedicine online, 2016 - Elsevier
Several studies have attempted to explain the high overall prevalence of polycystic ovary
syndrome among women worldwide (about 4–10%) despite its link to subfertile phenotypes …

Single-nucleotide polymorphism on exon 17 of insulin receptor gene influences insulin resistance in PCOS: a pilot study on north Indian women

S Gangopadhyay, N Agrawal, A Batra, BC Kabi… - Biochemical …, 2016 - Springer
Polycystic ovarian syndrome (PCOS), a major cause of infertility, is also strongly associated
with insulin resistance. Defects in insulin receptor signaling are considered as one of the …

A cross-sectional study to assess any possible linkage of C/T polymorphism in CYP17A1 gene with insulin resistance in non-obese women with polycystic ovarian …

U Banerjee, A Dasgupta, A Khan… - Indian Journal of …, 2016 - journals.lww.com
Methods: Polymorphism study was performed by restriction fragment length polymorphism
(RFLP) analysis of the Msp A1 digest of the PCR product of the target gene in 75 PCOS …

Polymorphisms and haplotypes of insulin-like factor 3 gene are associated with risk of polycystic ovary syndrome in Indian women

N Shaikh, R Dadachanji, P Meherji, N Shah… - Gene, 2016 - Elsevier
Background Insulin-like factor 3 (INSL3), secreted by the ovarian theca cells is involved in
androgen production, follicular growth and oocyte maturation. Both androgens and INSL3 …

胰岛素受体基因外显子17 His 1058 位点rs1799817C→ T 多态性与多囊卵巢综合征关系的系统评价

蒋天从, 易建平, 韩宝生, 戚桂杰, 姚满红, 郭璐莹 - 山东医药, 2016 - cqvip.com
目的系统评价胰岛素受体(INSR) 基因外显子17His1058 位点rs1799817C→ T
多态性与多囊卵巢综合征(PCOS) 的关系. 方法检索Pub Med, Ovid, EMBASE …

多囊卵巢综合征遗传学病因研究进展

刘璐茜, 张丹英, 刘益群, 李安吉, 俞超芹 - 辽宁中医药大学学报, 2016 - cqvip.com
多囊卵巢综合征(Polycystic ovary syndrome, PCOS) 是育龄期妇女常见的生殖内分泌紊乱性
疾病, 其临床表现高度异质性, 主要内分泌特征为高雄激素血症, 高胰岛素血症. 目前, PCOS …

多囊卵巢综合征相关基因多态性研究进展

张帆, 韦继红 - 中国优生与遗传杂志, 2016 - cqvip.com
多囊卵巢综合征(PCOS) 是育龄期妇女常见的内分泌紊乱性疾病, 有高雄激素,
高胰岛素和胰岛素抵抗等特征, 存在多种远期健康风险, 是妇科内分泌疾病中最具争议的疾病之 …