Systematic review of factors influencing extracellular vesicle yield from cell cultures

JM Gudbergsson, KB Johnsen, MN Skov, M Duroux - Cytotechnology, 2016 - Springer
The potential therapeutic utility of extracellular vesicles (EVs) has spawned an interest into a
scalable production, where the quantity and purity of EV samples is sufficient for clinical …

Low-density lipoprotein mimics blood plasma-derived exosomes and microvesicles during isolation and detection

BW Sódar, Á Kittel, K Pálóczi, KV Vukman… - Scientific reports, 2016 - nature.com
Circulating extracellular vesicles have emerged as potential new biomarkers in a wide
variety of diseases. Despite the increasing interest, their isolation and purification from body …

Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

SAA Kooijmans, CG Aleza, SR Roffler… - Journal of …, 2016 - Taylor & Francis
Background Extracellular vesicles (EVs) are attractive candidate drug delivery systems due
to their ability to functionally transport biological cargo to recipient cells. However, the …

Extracellular vesicles in cardiovascular disease: are they Jedi or Sith?

X Osteikoetxea, A Németh, BW Sódar… - The Journal of …, 2016 - Wiley Online Library
In the recent past, extracellular vesicles have become recognized as important players in
cell biology and biomedicine. Extracellular vesicles, including exosomes, microvesicles and …

Dual-wavelength surface plasmon resonance for determining the size and concentration of sub-populations of extracellular vesicles

DLM Rupert, GV Shelke, G Emilsson… - Analytical …, 2016 - ACS Publications
Accurate concentration determination of subpopulations of extracellular vesicles (EVs), such
as exosomes, is of importance both in the context of understanding their fundamental …

The growth determinants and transport properties of tunneling nanotube networks between B lymphocytes

A Osteikoetxea-Molnár, E Szabó-Meleg… - Cellular and Molecular …, 2016 - Springer
Tunneling nanotubes (TNTs) are long intercellular connecting structures providing a special
transport route between two neighboring cells. To date TNTs have been reported in different …

Glycosyl-phosphatidyl-inositol (GPI)-anchors and metalloproteases: their roles in the regulation of exosome composition and NKG2D-mediated immune recognition

S López-Cobo, C Campos-Silva… - Frontiers in cell and …, 2016 - frontiersin.org
Communication within the immune system depends on the release of factors that can travel
and transmit information at points distant from the cell that produced them. In general …