[HTML][HTML] Natural products as a vital source for the discovery of cancer chemotherapeutic and chemopreventive agents

GM Cragg, JM Pezzuto - Medical Principles and Practice, 2016 - karger.com
Throughout history, natural products have played a dominant role in the treatment of human
ailments. For example, the legendary discovery of penicillin transformed global existence …

Food antioxidants and their anti-inflammatory properties: a potential role in cardiovascular diseases and cancer prevention

K Griffiths, BB Aggarwal, RB Singh, HS Buttar, D Wilson… - Diseases, 2016 - mdpi.com
Mediterranean-style diets caused a significant decline in cardiovascular diseases (CVDs) in
early landmark studies. The effect of a traditional Mediterranean diet on lipoprotein oxidation …

Polyphenols as modulator of oxidative stress in cancer disease: new therapeutic strategies

AM Mileo, S Miccadei - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Cancer onset and progression have been linked to oxidative stress by increasing DNA
mutations or inducing DNA damage, genome instability, and cell proliferation and therefore …

Botanicals and their bioactive phytochemicals for women's health

BM Dietz, A Hajirahimkhan, TL Dunlap… - Pharmacological reviews, 2016 - ASPET
Botanical dietary supplements are increasingly popular for women's health, particularly for
older women. The specific botanicals women take vary as a function of age. Younger …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

[HTML][HTML] DNA methylation markers for oral pre-cancer progression: A critical review

K Shridhar, GK Walia, A Aggarwal, S Gulati, AV Geetha… - Oral oncology, 2016 - Elsevier
Although oral cancers are generally preceded by a well-established pre-cancerous stage,
there is a lack of well-defined clinical and morphological criteria to detect and signal …

Synergism of curcumin and cytarabine in the down regulation of multi-drug resistance genes in acute myeloid leukemia

K Shah, S Mirza, U Desai, N Jain… - Anti-Cancer Agents in …, 2016 - ingentaconnect.com
Background: The aim of the study was to find a role of Curcumin from natural source to
overcome drug resistance as well as to reduce cytotoxicity profile of the drug in Acute …

Nutritional epigenetics and the prevention of hepatocellular carcinoma with bioactive food constituents

FS Moreno, R Heidor, IP Pogribny - Nutrition and cancer, 2016 - Taylor & Francis
Hepatocellular carcinoma (HCC) is an aggressive and life-threatening disease often
diagnosed at intermediate or advanced stages, which substantially limits therapeutic …

The microbiota as an epigenetic control mechanism

BA Shenderov - The human microbiota and chronic disease …, 2016 - Wiley Online Library
This chapter concentrates on the potential role of the microbiota as a source of epigenetic
factors in the regulation of mammalian development, health, chronic metabolic diseases …

Anacardic acid, salicylic acid, and oleic acid differentially alter cellular bioenergetic function in breast cancer cells

BN Radde, N Alizadeh‐Rad, SM Price… - Journal of Cellular …, 2016 - Wiley Online Library
Anacardic acid is a dietary and medicinal phytochemical that inhibits breast cancer cell
proliferation and uncouples oxidative phosphorylation (OXPHOS) in isolated rat liver …