Alzheimer's disease is a progressive loss of memory and cognition, for which there is no
cure. Although genetic studies initially suggested a primary role for amyloid-in Alzheimer's …

Alzheimer's disease (AD) is a progressive, neurodegenerative disease and the most
common form of dementia in elderly people. It is an emerging public health problem that …

One of the shared hallmarks of neurodegenerative diseases is the accumulation of
misfolded proteins. Therefore, it is suspected that normal proteostasis is crucial for neuronal …

Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with
deposition of large amounts of amyloid within the central nervous system. Amyloid …

Alzheimer's disease (AD) is the most common form of age-related neurodegenerative
dementia, and it is estimated that over 5 million people currently have AD within United …

Neurodegenerative disorder such as Alzheimer's is most common form of memory loss
observed on aging population. The genetic factors are strongly influenced by risk of …

Alzheimer's disease (AD) is a neurodegenerative condition affecting approximately 30
million people worldwide. The abnormal build-up of amyloid beta (Aβ) peptide has been …

Alzheimer's disease (AD) causes a devastating loss of memory and cognition for which there
is no cure. Without effective treatments that slow or reverse the course of the disease, the …

The brain uses a special feature, synaptic plasticity, for learning and memory. As forms of
synaptic plasticity, associative plasticity, long-term potentiation (LTP) and long-term …