Self-assembly of macromolecules on multilayered polymer surfaces

PJ Yoo, KT Nam, J Qi, SK Lee, J Park… - US Patent …, 2016 - Google Patents
The invention is directed toward systems and methods for the formation of two dimensional
monolayer structures of ordered biomacromolecules, such as viruses, atop cohesive …

Erythrocyte-binding therapeutics

JA Hubbell, S Kontos, KY Dane - US Patent 9,518,087, 2016 - Google Patents
5,358,857 A 10/1994 Stengelin et al. 5,470,570 A 11/1995 Taylor et al. 5.487, 890 A 1/1996
Taylor et al. 5,879,679 A 3/1999 Taylor et al. 5,885,808 A 3/1999 Spooner et al. 5,886,143 A …

Erythrocyte-binding therapeutics

JA Hubbell, S Kontos, KY Dane - US Patent 9,517,257, 2016 - Google Patents
Peptides that specifically bind erythrocytes are described. These are provided as peptidic
ligands having sequences that specifically bind, or as antibodies or fragments thereof that …

Isolation and use of solid tumor stem cells

MF Clarke, SJ Morrison, MS Wicha, M Al-Hajj - US Patent 9,492,538, 2016 - Google Patents
5,643,765 A 7/1997 Willey 6,894,522 B2 5/2005 Averill et al. 5,648.464 A 7/1997 Artavanis-
Tsakonas et al. 7,115,360 B2 10/2006 Clarke et al. 5,650,317 A 7, 1997 Chang et al …

Priming of pluripotent stem cells for neural differentiation

N Meyer, M George, C Stankewicz, D Rajesh - US Patent 9,487,752, 2016 - Google Patents
A variety of different methods and compositions are described herein. Certain embodiments
concern several important advantages that improve the stem cell differen tiation process. It …

Frizzled-binding agents and uses thereof

AL Gurney - US Patent 9,499,630, 2016 - Google Patents
RCINICONZNJXQF-MZXODVADSA-N Intaxel Chemical compound O ([C@@ H] 1 [C@@] 2
(C [C@@ H](C (C)= C (C2 (C) C)[C@ H](C ([C@] 2 (C)[C@@ H](O) C [C@ H] 3OC [C@] 3 …

Monoclonal antibodies against frizzled

AL Gurney, AK Sato, FT Axelrod, TC Hoey… - US Patent …, 2016 - Google Patents
2013-06-20 Assigned to ONCOMED PHARMACEUTICALS, INC. reassignment ONCOMED
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Methods of treating neuroendocrine tumors using frizzled-binding agents

RJ Stagg, J Dupont - US Patent 9,266,959, 2016 - Google Patents
RCINICONZNJXQF-MZXODVADSA-N Intaxel Chemical compound O ([C@@ H] 1 [C@@] 2
(C [C@@ H](C (C)= C (C2 (C) C)[C@ H](C ([C@] 2 (C)[C@@ H](O) C [C@ H] 3OC [C@] 3 …

Methods and monitoring of treatment with a Wnt pathway inhibitor

J Dupont, RJ Stagg - US Patent 9,359,444, 2016 - Google Patents
LOJFGJZQOKTUBR-XAQOOIOESA-N NC (N)= NCCC [C@@ H](C (O)= O) NC (= O) CNC (=
O) CNC (= O)[C@ H](CC (O)= O) NC (= O)[C@@ H](NC (= O)[C@@ H](NC (= O)[C …

Vectors encoding rod-derived cone viability factor

T Luo - US Patent 9,265,813, 2016 - Google Patents
Hoover, et al.,“DNAWorks: an automated method for designing oligonucleotides for PCR-
based gene synthesis'. Nucleic Acids Research, 2002, vol. 30, No. 10 e43. GenBank …