Metals play important roles in the human body, maintaining cell structure and regulating
gene expression, neurotransmission, and antioxidant response, to name a few. However …

Parkinson's disease is a neurodegenerative disease/synucleinopathy that develops slowly;
however, there is no efficient method of early diagnosis, nor is there a cure. Progressive …

Abstract After Alzheimer, Parkinson's disease (PD) is the second most common
neurodegenerative disorder. Alpha synuclein (SNCA) is deemed as a major component of …

Abstract α-Synuclein is a conserved, abundantly expressed protein that is partially localized
in pre-synaptic terminals in the central nervous system. The precise biological function (s) …

Synucleinopathies are a group of progressive disorders characterized by the abnormal
aggregation and accumulation of α-synuclein (aSyn), an abundant neuronal protein that can …

Parkinson's disease is the most common α-synucleinopathy, and increased levels of iron are
found in the substantia nigra of Parkinson's disease patients, but the potential interlink …

Parkinson's disease (PD) is a severe neurodegenerative disorder affecting movements. After
Alzheimer's disease, it is the most common form of neurodegeneration. PD is characterized …

Neurodegenerative diseases affect a significant portion of the aging population. Several
lines of evidence suggest a positive association between environmental exposures, which …

Alpha-synuclein has long been studied due to its involvement in the progression of
Parkinson's disease (PD), a common neurodegenerative disorder, although a consensus on …

The role of metal ions in protein folding and structure is a critical topic to a range of scientists
in numerous fields, particularly those working in structural biology and bioinorganic …