From Krebs to clinic: glutamine metabolism to cancer therapy

BJ Altman, ZE Stine, CV Dang - Nature Reviews Cancer, 2016 - nature.com
The resurgence of research into cancer metabolism has recently broadened interests
beyond glucose and the Warburg effect to other nutrients, including glutamine. Because …

Current status of long non-coding RNAs in human breast cancer

S Cerk, D Schwarzenbacher, JB Adiprasito… - International journal of …, 2016 - mdpi.com
Breast cancer represents a major health burden in Europe and North America, as recently
published data report breast cancer as the second leading cause of cancer related death in …

The oncoprotein HBXIP suppresses gluconeogenesis through modulating PCK1 to enhance the growth of hepatoma cells

H Shi, R Fang, Y Li, L Li, W Zhang, H Wang, F Chen… - Cancer letters, 2016 - Elsevier
Hepatitis B X-interacting protein (HBXIP) as an oncoprotein plays crucial roles in the
development of cancer, involving glucose metabolism reprogramming. In this study, we are …

Insights into the regulatory role of non-coding RNAs in cancer metabolism

FO Beltrán-Anaya, A Cedro-Tanda… - Frontiers in …, 2016 - frontiersin.org
Cancer represents a complex disease originated from alterations in several genes leading
to disturbances in important signaling pathways in tumor biology, favoring heterogeneity that …

CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function

CP Masamha, Z Xia, N Peart, S Collum, WEI Li… - RNA, 2016 - rnajournal.cshlp.org
Alternative polyadenylation (APA) and alternative splicing (AS) provide mRNAs with the
means to avoid microRNA repression through selective shortening or differential usage of …

Long non‐coding RNAs in cancer metabolism

ZD Xiao, L Zhuang, B Gan - BioEssays, 2016 - Wiley Online Library
Altered cellular metabolism is an emerging hallmark of cancer. Accumulating recent
evidence links long non‐coding RNAs (lncRNAs), a still poorly understood class of non …

[PDF][PDF] OncoLncs: long non-coding RNAs with oncogenic functions

E Bozgeyik, E Bayraktar, A Chavez-Reyes… - Mol …, 2016 - pdfs.semanticscholar.org
A decade before the discovery of non-coding transcripts, approximately 98% of the human
genome was known as “transcriptional noise” or “junk DNA”. However, with the recent …

[HTML][HTML] Altérations de l'épissage et maladies rares

P de la Grange - médecine/sciences, 2016 - medecinesciences.org
La majorité des gènes codant des protéines chez l'homme sont soumis à l'épissage
alternatif, le principal mécanisme permettant d'augmenter la diversité du transcriptome et du …

[引用][C] SNP 位点rs6983267 相关非编码RNAG/U 对结肠癌细胞转移活性的影响

蔡文臣, 郝小惠, 沈阳丽, 孟晨雪, 田洁, 郭志义 - 山东医药, 2016