Although most treatment algorithms in inflammatory bowel disease (IBD) begin with
classifying patients according to disease severity, no formal validated or consensus …

Therapeutic advances in the management of IBD have led to a paradigm shift in the
assessment of IBD disease activity. Beyond clinical remission, objective assessment of …

Background Ozanimod (RPC1063) is an oral agonist of the sphingosine-1-phosphate
receptor subtypes 1 and 5 that induces peripheral lymphocyte sequestration, potentially …

Background Endoscopic mucosal healing is an established treatment target for UC, yet the
value of achieving histological remission remains unclear. Aims To evaluate histological …

Objectives: Endoscopic remission in ulcerative colitis (UC) is associated with improved
clinical outcomes. We assessed whether histological remission predicts clinical outcomes …

Abstract Background and Aims: The Ulcerative Colitis Endoscopic Index of Severity (UCEIS)
and the Mayo endoscopic score (Mayo ES) are used to evaluate ulcerative colitis (UC) …

OBJECTIVES: Objective evidence of inflammation has been associated with the risk of
relapse in patients with ulcerative colitis (UC) who are in clinical remission. We compared …

Background Data regarding the correlation of histologic and endoscopic healing with fecal
calprotectin (FC) are conflicting. We examined how FC levels correlate with histological and …

Background Mucosal healing in ulcerative colitis leads to a decreased need for medication
and decreased risk of disease relapse and colectomy. Histological healing seems to …

Background Acute severe ulcerative colitis (ASUC) is a life‐threatening condition for which
optimal management strategies remain ill‐defined. Aim To review the evidence regarding …