MicroRNAs (miRNAs) are small non-coding RNA comprising approximately 19–25
nucleotides. miRNAs can act as tumour suppressors or oncogenes, and aberrant expression …

Opinion Statement Radioiodine refractory differentiated thyroid cancer (RAI-R DTC) is a
challenging malignancy with limited prognosis and treatment options. Recently, clinical trials …

Retinoic acid is a promising tool in adjuvant cancer therapies, including refractory thyroid
cancer, and its biological role is mediated by the retinoic acid receptor beta (RARβ) …

Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent
identification of genetic and epigenetic alterations present in almost all differentiated tumors …

The objective of the present study was to compare the effects of isotretinoin 9-cis (RA9-cis)
as a post-surgery treatment of thyroid carcinoma to a traditional treatment (doxorubicin) and …

The recapitulation of primary tumour heterogenity and the existence of a minor sub-
population of cancer cells, capable of initiating tumour growth in xenografts on serial …

131 I 难治性分化型甲状腺癌(radioiodine-refractory differentiated thyroid cancer, RR-DTC)
是目前甲状腺癌临床治疗领域的一大难题. 维甲酸类药物, 过氧化物酶体增殖物激活受体激动剂 …

Background: Isotretinoin is widely used in the treatment of acne. Aims: We investigated the
effects of isotretinoin on thyroid function tests and thyroid volume in acne patients. Methods …

Clinical management of radioiodine-refractory differentiated thyroid cancer (RR-DTC) is
extremely difficult. Re-differentiation compounds, such as retinoids, peroxisome proliferator …

Overview Abnormal differentiation is one of the main features of human cancers, especially
in hematological malignancies. Many aberrant genetic and epigenetic factors have been …