Water is an essential participant in the stability, structure, dynamics, and function of proteins
and other biomolecules. Thermodynamically, changes in the aqueous environment affect …

The bacterial chaperonin GroEL and its cofactor GroES constitute the paradigmatic
molecular machine of protein folding. GroEL is a large double-ring cylinder with ATPase …

Cold-active enzymes constitute an attractive resource for biotechnological applications.
Their high catalytic activity at temperatures below 25° C makes them excellent biocatalysts …

Amyloid-like protein aggregation is associated with neurodegeneration and other
pathologies. The nature of the toxic aggregate species and their mechanism of action …

Why do cells age? Recent advances show that the cytoplasm is organized into many
membrane‐less compartments via a process known as phase separation, which ensures …

The common underlying feature of most neurodegenerative diseases such as Alzheimer
disease (AD), prion diseases, Parkinson disease (PD), and amyotrophic lateral sclerosis …

It is increasingly recognized that molecular chaperones play a key role in modulating the
formation of amyloid fibrils, a process associated with a wide range of human disorders …

Nanomanufacturing, the commercially scalable and economically sustainable mass
production of nanoscale materials and devices, represents the tangible outcome of the …

The rising temperatures are resulting in heat stress for various agricultural crops to limit their
growth, metabolism, and leading to significant loss of yield potential worldwide. Heat stress …

The 90S pre-ribosome is an early biogenesis intermediate formed during co-transcriptional
ribosome formation, composed of∼ 70 assembly factors and several small nucleolar RNAs …