Neurogenesis in the developing and adult brain—similarities and key differences
M Götz, M Nakafuku, D Petrik - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Adult neurogenesis in the mammalian brain is often viewed as a continuation of
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
Inhibition of dopamine receptor D4 impedes autophagic flux, proliferation, and survival of glioblastoma stem cells
S Dolma, HJ Selvadurai, X Lan, L Lee, M Kushida… - Cancer cell, 2016 - cell.com
Glioblastomas (GBM) grow in a rich neurochemical milieu, but the impact of neurochemicals
on GBM growth is largely unexplored. We interrogated 680 neurochemical compounds in …
on GBM growth is largely unexplored. We interrogated 680 neurochemical compounds in …
Epigenetic regulations of GABAergic neurotransmission: relevance for neurological disorders and epigenetic therapy
S Shrestha, SM Offer - Medical Epigenetics, 2016 - karger.com
The GABAergic neurotransmission is a highly conserved system that has been attributed to
various regulatory events. There has been a notable number of studies on the importance of …
various regulatory events. There has been a notable number of studies on the importance of …
DNA methylation reactivates GAD1 expression in cancer by preventing CTCF-mediated polycomb repressive complex 2 recruitment
H Yan, G Tang, H Wang, L Hao, T He, X Sun, AH Ting… - Oncogene, 2016 - nature.com
Levels of γ-aminobutyric acid (GABA) and glutamic acid decarboxylase 1 (GAD1), the
enzyme that synthesizes GABA, are significantly increased in neoplastic tissues. However …
enzyme that synthesizes GABA, are significantly increased in neoplastic tissues. However …
A mi RNA s panel promotes the proliferation and invasion of colorectal cancer cells by targeting GABBR 1
Y Longqiu, L Pengcheng, F Xuejie, Z Peng - Cancer medicine, 2016 - Wiley Online Library
Micro RNA s (mi RNA s) have been implicated in the regulation of colorectal cancer. Despite
the expression of miR‐17‐92 cluster in cancer has been gradually revealed, the role of each …
the expression of miR‐17‐92 cluster in cancer has been gradually revealed, the role of each …
Beyond epilepsy and autism: disruption of GABRB3 causes ocular hypopigmentation
RJ Delahanty, Y Zhang, TJ Bichell, W Shen, K Verdier… - Cell reports, 2016 - cell.com
Reduced ocular pigmentation is common in Angelman syndrome (AS) and Prader-Willi
syndrome (PWS) and is long thought to be caused by OCA2 deletion. GABRB3 is located in …
syndrome (PWS) and is long thought to be caused by OCA2 deletion. GABRB3 is located in …
[HTML][HTML] Glutamate decarboxylase 1 overexpression as a poor prognostic factor in patients with nasopharyngeal carcinoma
YY Lee, TB Chao, MJ Sheu, YF Tian, TJ Chen… - Journal of …, 2016 - ncbi.nlm.nih.gov
Background: Glutamate decarboxylase 1 (GAD1) which serves as a rate-limiting enzyme
involving in the production of γ-aminobutyric acid (GABA), exists in the GABAergic neurons …
involving in the production of γ-aminobutyric acid (GABA), exists in the GABAergic neurons …
Propofol inhibits T-helper cell type-2 differentiation by inducing apoptosis via activating gamma-aminobutyric acid receptor
J Meng, X Xin, Z Liu, H Li, B Huang, Y Huang… - Journal of Surgical …, 2016 - Elsevier
Background Propofol has been shown to attenuate airway hyperresponsiveness in asthma
patients. Our previous study showed that it may alleviate lung inflammation in a mouse …
patients. Our previous study showed that it may alleviate lung inflammation in a mouse …
Sevoflurane represses the self‐renewal ability by regulating miR‐7a, 7b/Klf4 signalling pathway in mouse embryonic stem cells
Q Wang, G Li, B Li, Q Chen, D Lv, J Liu, J Ma… - Cell …, 2016 - Wiley Online Library
Sevoflurane is a frequently‐used clinical inhalational anaesthetic and can cause toxicity to
embryos during foetal development. Embryonic stem cells (ESC s) are derived from the …
embryos during foetal development. Embryonic stem cells (ESC s) are derived from the …
ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent …
A Omelyanenko, P Sekyrova, M Andäng - Springerplus, 2016 - Springer
Pluripotent stem cells are the starting cell type of choice for the development of many cell-
based regenerative therapies due to their rapid and unlimited proliferation and broad …
based regenerative therapies due to their rapid and unlimited proliferation and broad …