Enzymes have the potential to catalyse a wide variety of chemical reactions. They are
increasingly being sought as environmentally friendly and cost‐effective alternatives to …

The utilization of continuous-flow biochemical reactors, including biocatalysis,
biotransformation, and biochemical interaction based flow-analytical systems, and enzyme …

The local flexibility of an enzyme's active center plays pivotal roles in catalysis, however,
little is known about how the flexibility of these flexible residues affects stability. In this study …

The adaptation of microorganisms to extreme living temperatures requires the evolution of
enzymes with a high catalytic efficiency under these conditions. Such extremophilic …

Green Biocatalysis presents an exciting green technology that uses mild and safe processes
with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient …

Biocatalyst discovery and directed evolution are central to many pharmaceutical research
programs, yet the lack of robust high-throughput screening methods for large libraries of …

While enzymes are valuable tools in many fields of biotechnology, they are fragile and must
be protected against denaturing conditions such as unfavorable solution pH. Within living …

Deracemization via oxidoreductive stereoinversion is one of the most attractive methods for
the preparation of enantiomerically pure compounds. However, available enzymatic system …

Background Candida parapsilosis (R)-carbonyl reductase (RCR) and (S)-carbonyl
reductase (SCR) are involved in the stereoconversion of racemic (R, S)-1-phenyl-1, 2 …

Integration of biocatalysis in synthetic route for the development of pharmaceutical
intermediates and active pharmaceutical ingredients (APIs) holds great promise, as evident …