[HTML][HTML] Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question
EV Koonin, P Starokadomskyy - Studies in history and philosophy of …, 2016 - Elsevier
The question whether or not “viruses are alive” has caused considerable debate over many
years. Yet, the question is effectively without substance because the answer depends …
years. Yet, the question is effectively without substance because the answer depends …
Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA
Mosquito-borne flaviviruses, including yellow fever virus (YFV), Zika virus (ZIKV), and West
Nile virus (WNV), profoundly affect human health. The successful transmission of these …
Nile virus (WNV), profoundly affect human health. The successful transmission of these …
Inactivation of the type I interferon pathway reveals long double‐stranded RNA‐mediated RNA interference in mammalian cells
PV Maillard, AG Van der Veen… - The EMBO …, 2016 - embopress.org
RNA interference (RNA i) elicited by long double‐stranded (ds) or base‐paired viral RNA
constitutes the major mechanism of antiviral defence in plants and invertebrates. In contrast …
constitutes the major mechanism of antiviral defence in plants and invertebrates. In contrast …
The evolving world of small RNAs from RNA viruses
RNA virus infection in plants and invertebrates can produce virus‐derived small RNAs.
These RNAs share features with host endogenous small interfering RNAs (siRNAs). They …
These RNAs share features with host endogenous small interfering RNAs (siRNAs). They …
[HTML][HTML] A tale of two RNAs during viral infection: how viruses antagonize mRNAs and small non-coding RNAs in the host cell
KM Herbert, A Nag - Viruses, 2016 - mdpi.com
Viral infection initiates an array of changes in host gene expression. Many viruses dampen
host protein expression and attempt to evade the host anti-viral defense machinery. Host …
host protein expression and attempt to evade the host anti-viral defense machinery. Host …
Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response
EA Brettmann, JS Shaik, H Zangger… - Proceedings of the …, 2016 - National Acad Sciences
Many Leishmania (Viannia) parasites harbor the double-stranded RNA virus Leishmania
RNA virus 1 (LRV1), which has been associated with increased disease severity in animal …
RNA virus 1 (LRV1), which has been associated with increased disease severity in animal …
Two amino acids near the N‐terminus of Cucumber mosaic virus 2b play critical roles in the suppression of RNA silencing and viral infectivity
K Dong, Y Wang, Z Zhang, LX Chai… - Molecular plant …, 2016 - Wiley Online Library
Cucumber mosaic virus (CMV) 2b suppresses RNA silencing primarily through the binding
of double‐stranded RNA (dsRNA) of varying sizes. However, the biologically active form of …
of double‐stranded RNA (dsRNA) of varying sizes. However, the biologically active form of …
Characterization and function of Tomato yellow leaf curl virus-derived small RNAs generated in tolerant and susceptible tomato varieties
BAI Miao, G YANG, W CHEN, R LIN, L Jian… - Journal of integrative …, 2016 - Elsevier
Virus-tolerant plant, which allows the accumulation of virus and then generates virus-derived
small RNAs (vsRNAs), is a valuable material to reveal the antiviral efficiency of vsRNAs …
small RNAs (vsRNAs), is a valuable material to reveal the antiviral efficiency of vsRNAs …
Critical regions and residues for self-interaction of grapevine leafroll-associated virus 2 protein p24
Q Liu, R Guo, M Li, M Feng, X Wang, Q Wang, Y Cheng - Virus research, 2016 - Elsevier
Abstract The 24-kDa protein (p24) encoded by grapevine leafroll-associated virus 2 (GLRaV-
2) is an RNA-silencing suppressor. In this work, a yeast two-hybrid system (YTHS) and …
2) is an RNA-silencing suppressor. In this work, a yeast two-hybrid system (YTHS) and …
[HTML][HTML] Helper component-proteinase and coat protein are involved in the molecular processes of potato virus A translation and replication
A Lõhmus - 2016 - helda.helsinki.fi
Potato virus A (PVA), a positive-strand RNA ([+] RNA) virus, belongs to the genus Potyvirus,
which is the largest RNA virus group in plants. Like all (+) RNA viruses of eukaryotes …
which is the largest RNA virus group in plants. Like all (+) RNA viruses of eukaryotes …