Chronic pain conditions are multifactorial disorders with a high frequency in the population.
Their pathophysiology is often unclear, and treatment is inefficient. During the last 20 years …

Genomic technologies have evolved rapidly contributing to the understanding of diseases.
Genome-wide association studies (GWAS) and whole-exome sequencing have aided the …

Breast cancer is the most common female cancer, affecting approximately one in eight
women during their life-time. Besides environmental triggers and hormones, inherited …

Osteoporosis is characterized by low bone mass and an increased risk of fracture. Genetic
factors, environmental factors and gene–environment interactions all contribute to a person's …

Detecting the molecular basis of adaptation is one of the major questions in population
genetics. With the advance in sequencing technologies, nearly complete interrogation of …

Bone mineral density (BMD) is a quantitative traits used as a surrogate phenotype for the
diagnosis of osteoporosis, a common metabolic disorder characterized by increased fracture …

Background Improving meat quality including taste and tenderness is critical to the
protection and development of markets for sheep meat. Phenotypic selection for such …

Genome-wide association studies (GWAS) have identified markers within the WNT4 region
on chromosome 1p36. 12 showing consistent and strong association with increasing …

During growth, individual skull bones overlap at sutures, where osteoblast differentiation
and bone deposition occur. Mutations causing skull malformations have revealed some …

Bone mineral density (BMD) is a measure of osteoporosis and is useful in evaluating the risk
of fracture. In a genome-wide association study of BMD among 20,100 Icelanders, with …