Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination

MJ Fox, AL Mosley - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
The yeast RNA exosome is a eukaryotic ribonuclease complex essential for RNA
processing, surveillance, and turnover. It is comprised of a barrel‐shaped core and cap as …

[HTML][HTML] Recent advances in understanding transcription termination by RNA polymerase II

TJ Loya, D Reines - F1000Research, 2016 - ncbi.nlm.nih.gov
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …

Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in …

SK Sariki, PK Sahu, U Golla, V Singh… - The FEBS …, 2016 - Wiley Online Library
Mutations in the Senataxin gene, SETX are known to cause the neurodegenerative
disorders, ataxia with oculomotor apraxia type 2 (AOA 2), and amyotrophic lateral sclerosis 4 …

[HTML][HTML] Determinants of amyloid formation for the yeast termination factor Nab3

TW O'Rourke, D Reines - PLoS One, 2016 - journals.plos.org
Low complexity protein sequences are often intrinsically unstructured and many have the
potential to polymerize into amyloid aggregates including filaments and hydrogels. RNA …

Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae

EA Raupach, JA Martens… - G3: Genes, Genomes …, 2016 - academic.oup.com
Transcription of nonprotein-coding DNA is widespread in eukaryotes and plays important
regulatory roles for many genes, including genes that are misregulated in cancer cells. Its …

[PDF][PDF] RNA polymerase II [version 1; peer review: 2 approved]

TJ Loya, D Reines - 2016 - pdfs.semanticscholar.org
Transcription termination is a fundamental process in which RNA polymerase ceases RNA
chain extension and dissociates from the chromatin template, thereby defining the end of the …

Analysis of non-protein coding DNA transcription for roles in regulating gene expression

E Raupach - 2016 - d-scholarship.pitt.edu
During transcription, the DNA sequence encoding a gene is “read” and copied into an RNA
molecule. Many RNA molecules convey instructions for synthesizing proteins. Traditionally …

[PDF][PDF] Genetic and genomic analysis of RNA polymerase II backtracking in saccharomyces cerevisiae

MD Miguel Jiménez - 2016 - idus.us.es
Transcription is a cellular process by which an RNA molecule is synthesised from a DNA
template. The central element of this process is the RNA polymerase, the enzyme that …

Structural and functional studies of the transcriptional regulator Seb1 in fission yeast

S Wittmann - 2016 - ora.ox.ac.uk
RNA polymerase II (Pol II) is responsible for the transcription of all protein-coding and some
non-coding genes in eukaryotes. Its largest subunit, Rpb1, contains a unique C-terminal …

[PDF][PDF] Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic

EA Raupach, JA Martens, KM Arndt - 2016 - scienceopen.com
Transcription of nonprotein-coding DNA is widespread in eukaryotes and plays important
regulatory roles for many genes, including genes that are misregulated in cancer cells. Its …