Myeloproliferative neoplasms: Current molecular biology and genetics
K Saeidi - Critical reviews in oncology/hematology, 2016 - Elsevier
Myeloproliferative neoplasms (MPNs) are clonal disorders characterized by increased
production of mature blood cells. Philadelphia chromosome-negative MPNs (Ph-MPNs) …
production of mature blood cells. Philadelphia chromosome-negative MPNs (Ph-MPNs) …
Diagnosis and treatment of juvenile myelomonocytic leukemia
K Sakashita, K Matsuda, K Koike - Pediatrics International, 2016 - Wiley Online Library
Juvenile myelomonocytic leukemia (JMML) is a rare myelodysplastic/myeloproliferative
disorder that occurs during infancy and early childhood; this disorder is characterized by …
disorder that occurs during infancy and early childhood; this disorder is characterized by …
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO
S Goyama, J Schibler, A Gasilina, M Shrestha, S Lin… - Leukemia, 2016 - nature.com
Abstract The t (8; 21) rearrangement, which creates the AML1-ETO fusion protein,
represents the most common chromosomal translocation in acute myeloid leukemia (AML) …
represents the most common chromosomal translocation in acute myeloid leukemia (AML) …
[HTML][HTML] Биология миелопролиферативных новообразований
АЛ Меликян, ИН Суборцева - … Фундаментальные исследования и …, 2016 - cyberleninka.ru
Хронические миелопролиферативные заболевания (ВОЗ, 2001), или
миелопролиферативные новообразования/опухоли (МПН)(ВОЗ, 2008), являются …
миелопролиферативные новообразования/опухоли (МПН)(ВОЗ, 2008), являются …
Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia
ABSTRACT A-kinase anchor protein 12 (AKAP12) is a regulator of protein kinase A and
protein kinase C signaling, acting downstream of RAS. Epigenetic silencing of AKAP12 has …
protein kinase C signaling, acting downstream of RAS. Epigenetic silencing of AKAP12 has …
[HTML][HTML] MicroRNA fingerprints in juvenile myelomonocytic leukemia (JMML) identified miR-150-5p as a tumor suppressor and potential target for treatment
PP Leoncini, A Bertaina, D Papaioannou, C Flotho… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Juvenile myelomonocytic leukemia (JMML) is an aggressive leukemia of early childhood
characterized by aberrant proliferation of myelomonocytic cells and hypersensitivity to GM …
characterized by aberrant proliferation of myelomonocytic cells and hypersensitivity to GM …
[HTML][HTML] Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2−/− γc−/− mice
CF Krombholz, K Aumann, M Kollek, D Bertele… - …, 2016 - ncbi.nlm.nih.gov
Juvenile myelomonocytic leukemia is a clonal malignant disease affecting young children.
Current cure rates, even with allogeneic hematopoietic stem cell transplantation, are no …
Current cure rates, even with allogeneic hematopoietic stem cell transplantation, are no …
[HTML][HTML] Biology of myeloproliferative malignancies
AL Melikyan, IN Subortseva - … . Fundamentalnye issledovaniya I …, 2016 - old.bloodjournal.ru
ABSTRACT Chronic myeloproliferative diseases (WHO, 2001), or myeloproliferative
neoplasms/malignancies (MPN)(WHO, 2008), are clonal diseases characterized by …
neoplasms/malignancies (MPN)(WHO, 2008), are clonal diseases characterized by …
Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy
Juvenile myelomonocytic leukemia (JMML) is an aggressive pediatric mixed
myelodysplastic/myeloproliferative neoplasm (MDS/MPN). JMML leukemogenesis is linked …
myelodysplastic/myeloproliferative neoplasm (MDS/MPN). JMML leukemogenesis is linked …
[HTML][HTML] VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease
W An, BC Mohapatra, N Zutshi, TA Bielecki, BT Goez… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract CBL and CBL-B ubiquitin ligases play key roles in hematopoietic stem cell
homeostasis and their aberrations are linked to leukemogenesis. Mutations of CBL, often …
homeostasis and their aberrations are linked to leukemogenesis. Mutations of CBL, often …