Basic experimental stem cell research has opened up the possibility of many diverse clinical
applications; however, translation to clinical trials has been restricted to only a few diseases …

Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …

Transplantation of pluripotent stem cells and their differentiated progeny has the potential to
preserve or regenerate functional pathways and improve function after central nervous …

Despite the vast improvements of cell therapy in spinal cord injury treatment, no optimum
protocol has been developed for application of neural stem/progenitor cells. In this regard …

Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow
improves behavioral function in rat models of spinal cord injury (SCI). However, most studies …

Stem cells are a promising solution for the treatment of a variety of diseases. However, the
limited survival and engraftment of transplanted cells due to a hostile ischemic environment …

Traumatic brain injury (TBI) in humans can result in permanent tissue damage and has been
linked to cognitive impairment that lasts years beyond the initial insult. Clinically effective …

Abstract Spinal Cord Injury (SCI) is a highly incapacitating condition for which there is still no
cure. Current clinical approaches are mainly based on palliative care, so there is a need to …

Olfactory ensheathing cell (OEC) transplantation is a candidate cellular treatment approach
for human spinal cord injury (SCI) due to their unique regenerative potential and autologous …