[HTML][HTML] Long noncoding RNAs in cancer pathways

AM Schmitt, HY Chang - Cancer cell, 2016 - cell.com
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional
mutations within the noncoding genome, with profound effects on the expression of long …

TUG 1: a pivotal oncogenic long non‐coding RNA of human cancers

Z Li, J Shen, MTV Chan, WKK Wu - Cell proliferation, 2016 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are a group greater than 200 nucleotides in length. An
increasing number of studies has shown that lnc RNA s play important roles in diverse …

[HTML][HTML] Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment

K Katsushima, A Natsume, F Ohka, K Shinjo… - Nature …, 2016 - nature.com
Targeting self-renewal is an important goal in cancer therapy and recent studies have
focused on Notch signalling in the maintenance of stemness of glioma stem cells (GSCs) …

LncRNA TUG1 acts as a tumor suppressor in human glioma by promoting cell apoptosis

J Li, M Zhang, G An, Q Ma - Experimental Biology and …, 2016 - journals.sagepub.com
Previous studies have revealed multiple functional roles of long non-coding RNA taurine
upregulated gene 1 in different types of malignant tumors, except for human glioma. Here, it …

LncRNA‐ATB mediated E‐cadherin repression promotes the progression of colon cancer and predicts poor prognosis

B Yue, S Qiu, S Zhao, C Liu, D Zhang… - Journal of …, 2016 - Wiley Online Library
Background Long non‐coding RNA‐activated by TGF‐β (lncRNA‐ATB) promotes the
invasion–metastasis cascade in hepatocellular carcinoma via downregulating E‐cadherin …

[HTML][HTML] Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung …

W Li, M Sun, C Zang, P Ma, J He, M Zhang… - Cell death & …, 2016 - nature.com
Recently, long non-coding RNAs (lncRNAs) are identified as new crucial regulators of
diverse cellular processes, including cell proliferation, differentiation and cancer cells …

[HTML][HTML] Increased expression of long noncoding RNA TUG1 predicts a poor prognosis of gastric cancer and regulates cell proliferation by epigenetically silencing of …

E Zhang, X He, D Yin, L Han, M Qiu, T Xu, R Xia… - Cell death & …, 2016 - nature.com
Recent evidence highlights long noncoding RNAs (lncRNAs) as crucial regulators of cancer
biology that contribute to tumorigenesis. LncRNA TUG1 was initially detected in a genomic …

[HTML][HTML] The long non-coding RNA TUG1 indicates a poor prognosis for colorectal cancer and promotes metastasis by affecting epithelial-mesenchymal transition

J Sun, C Ding, Z Yang, T Liu, X Zhang, C Zhao… - Journal of translational …, 2016 - Springer
Background Long intergenic non-coding RNAs (lncRNAs) are a class of non-coding RNAs
that are involved in gene expression regulation. Taurine up-regulated gene 1 (TUG1) is a …

Downregulation of long noncoding RNA Meg3 affects insulin synthesis and secretion in mouse pancreatic beta cells

LH You, N Wang, DD Yin, LT Wang… - Journal of cellular …, 2016 - Wiley Online Library
Increasing evidence indicates that long noncoding RNAs (lncRNAs) are involved in diverse
biological process. Mouse maternal expressed gene 3 (Meg3) is an imprinted gene and …

Long non-coding RNAs and their roles in non-small-cell lung cancer

MM Wei, GB Zhou - Genomics, Proteomics and Bioinformatics, 2016 - academic.oup.com
As a leading cause of cancer deaths worldwide, lung cancer is a collection of diseases with
diverse etiologies which can be broadly classified into small-cell lung cancer (SCLC) and …