TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
Abstract Toll/IL-1R domain-containing adaptor-inducing IFN-β (TRIF)-dependent signaling is
required for TLR-mediated production of type-I IFN and several other proinflammatory …
required for TLR-mediated production of type-I IFN and several other proinflammatory …
Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies
Malignancies of mature B cells are quite distinctive in originating from well-differentiated
cells. Hence, it is not paradoxical that, similar to their normal counterparts, most mature B …
cells. Hence, it is not paradoxical that, similar to their normal counterparts, most mature B …
Mechanism of action of probiotic bacteria on intestinal and systemic immunities and antigen-presenting cells
FLY Fong, NP Shah, P Kirjavainen… - … Reviews of Immunology, 2016 - Taylor & Francis
Immunomodulation has been shown to be one of the major functions of probiotic bacteria.
This review is presented to provide detailed information on the immunomodulatory …
This review is presented to provide detailed information on the immunomodulatory …
[HTML][HTML] A Standardized Chemically Modified Curcuma longa Extract Modulates IRAK-MAPK Signaling in Inflammation and Potentiates Cytotoxicity
The TLR/IL-1R pathway is a critical signaling module that is misregulated in pathologies like
inflammation and cancer. Extracts from turmeric (Curcuma longa L.) enriched in curcumin …
inflammation and cancer. Extracts from turmeric (Curcuma longa L.) enriched in curcumin …
[HTML][HTML] The LXR ligand GW3965 inhibits Newcastle disease virus infection by affecting cholesterol homeostasis
X Sheng, Y Sun, Y Zhan, Y Qu, H Wang, M Luo… - Archives of …, 2016 - Springer
Newcastle disease (ND) is a contagious disease that affects most species of birds. Its
causative pathogen, Newcastle disease virus (NDV), also exhibits considerable oncolytic …
causative pathogen, Newcastle disease virus (NDV), also exhibits considerable oncolytic …
Interrogating Raf-1 Kinase Inhibitor Protein (RKIP) as a Novel Therapeutic Target for Modulating Inflammatory Responses
KT Wright - 2016 - digitalcommons.lib.uconn.edu
The studies presented here were designed to test if Raf-1 kinase inhibitor protein (RKIP)
plays a functionally significant role in immunity, and to interrogate its possibility of providing …
plays a functionally significant role in immunity, and to interrogate its possibility of providing …
[图书][B] Detection and characterization of lipopeptide-specific T cells in guinea pigs sensitized with bacteria of the Mycobacterium tuberculosis complex
E Kaufmann - 2016 - jlupub.ub.uni-giessen.de
The only available vaccine against TB the Bacille Calmette-Guérin (BCG) vaccine provides
reliable protection against severe manifestations of childhood TB, but not against pulmonary …
reliable protection against severe manifestations of childhood TB, but not against pulmonary …