[HTML][HTML] Revealing eltrombopag's promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation

CA Di Buduo, M Currao, A Pecci, DL Kaplan… - …, 2016 - ncbi.nlm.nih.gov
Eltrombopag is a small, non-peptide thrombopoietin mimetic that has been approved for
increasing platelet count not only in immune thrombocytopenia and Hepatitis C virus-related …

STAT3 inhibitors in cancer: a comprehensive update

U Bharadwaj, MM Kasembeli, DJ Tweardy - STAT Inhibitors in Cancer, 2016 - Springer
STAT3 is an important signaling molecule that modulates a wide range of genes by relaying
extracellular signals from the plasma membrane to the nucleus in response to peptide …

[HTML][HTML] Tyrosine 625 plays a key role and cooperates with tyrosine 630 in MPL W515L-induced signaling and myeloproliferative neoplasms

C Yu, Q Yang, Y Chen, D Wang, R Levine, J Crispino… - Cell & Bioscience, 2016 - Springer
Background Myeloproliferative neoplasms (MPN) are a group of blood cancers that boost
normal blood cell production in the bone marrow. Abnormal mutations in stem cells were …

[PDF][PDF] CONVERGENCE OF PKC AND JAK-STAT SIGNALING ON TRANSCRIPTION FACTOR GATA-4

J Wang, P Paradis, A Aries, H Komati, C Lefebvre… - academia.edu
CONVERGENCE OF PKC AND JAK-STAT SIGNALING ON TRANSCRIPTION FACTOR GATA-4
Running title: GATA-STAT interaction Jun Wang, Pierre Page 1 1 CONVERGENCE OF PKC AND …