Peroxisomes contain numerous enzymatic activities that are important for mammalian
physiology. Patients lacking either all peroxisomal functions or a single enzyme or …

It is increasingly understood that in the aging brain, especially in the case of patients
suffering from neurodegenerative diseases, some fatty acids at pathologically high …

Background Parkinson's disease (PD) is a progressive neurodegenerative disorder
characterized by motor and non-motor symptoms. The cause of the motor symptoms is the …

Accumulation of toxic metabolites has been described to inhibit mitochondrial enzymes,
thereby inducing oxidative stress in propionic acidemia (PA), an autosomal recessive …

Huntington's disease (HD) is a devastating illness and at present there is no disease
modifying therapy or cure for it; and management of the disease is limited to a few treatment …

Abstract X‐linked adrenoleukodystrophy (X‐ALD) is a progressive neurometabolic disease
caused by mutations/deletions in the Abcd1 gene. Similar mutations/deletions in the Abcd1 …

It is increasingly understood that in the aging brain, especially in the case of patients
suffering from neurodegenerative diseases, some fatty acids at pathologically high …

X-linked adrenoleukodystrophy (X-ALD) is the most frequent inherited monogenic
demyelinating disease. It is often lethal and currently lacks a satisfactory therapy. The …

In this thesis for the degree of PhD, cand. med. Morten Andreas Horn and his coworkers
have surveyed the Norwegian population of patients with X-linked adrenoleukodystrophy …

X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ATP binding cassette
subfamily D member 1 (ABCD1), a gene that encodes peroxisomal membrane located on …