Maternal immune activation: Implications for neuropsychiatric disorders
ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
[HTML][HTML] The genetics of stress-related disorders: PTSD, depression, and anxiety disorders
JW Smoller - Neuropsychopharmacology, 2016 - nature.com
Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …
factors: genetic vulnerability and environmental stressors. An important role for …
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
Almost all genetic risk factors for autism spectrum disorders (ASDs) can be found in the
general population, but the effects of this risk are unclear in people not ascertained for …
general population, but the effects of this risk are unclear in people not ascertained for …
Diagnosis of autism spectrum disorder: reconciling the syndrome, its diverse origins, and variation in expression
JN Constantino, T Charman - The lancet neurology, 2016 - thelancet.com
Recent discoveries about the pathogenesis and symptom structure of autism spectrum
disorders (ASDs) are challenging traditional nosology and driving efforts to reconceptualise …
disorders (ASDs) are challenging traditional nosology and driving efforts to reconceptualise …
Major depressive disorder
Major depressive disorder (MDD) is a debilitating disease that is characterized by
depressed mood, diminished interests, impaired cognitive function and vegetative …
depressed mood, diminished interests, impaired cognitive function and vegetative …
The promises and challenges of human brain organoids as models of neuropsychiatric disease
G Quadrato, J Brown, P Arlotta - Nature medicine, 2016 - nature.com
Neuropsychiatric disorders such as autism spectrum disorder (ASD), schizophrenia (SCZ)
and bipolar disorder (BPD) are of great societal and medical importance, but the complexity …
and bipolar disorder (BPD) are of great societal and medical importance, but the complexity …
Evidence-based guidelines for treating bipolar disorder: revised third edition recommendations from the British Association for Psychopharmacology
GM Goodwin, PM Haddad, IN Ferrier… - Journal of …, 2016 - journals.sagepub.com
The British Association for Psychopharmacology guidelines specify the scope and targets of
treatment for bipolar disorder. The third version is based explicitly on the available evidence …
treatment for bipolar disorder. The third version is based explicitly on the available evidence …
Psychiatric classifications: validity and utility
A Jablensky - World Psychiatry, 2016 - Wiley Online Library
Despite historical assumptions to the contrary, there is little evidence that the majority of
recognized mental disorders are separated by natural boundaries. Diagnostic categories …
recognized mental disorders are separated by natural boundaries. Diagnostic categories …
Top 10 replicated findings from behavioral genetics
In the context of current concerns about replication in psychological science, we describe 10
findings from behavioral genetic research that have replicated robustly. These are “big” …
findings from behavioral genetic research that have replicated robustly. These are “big” …