Proteins change their charge state through protonation and redox reactions as well as
through binding charged ligands. The free energy of these reactions is dominated by …

Understanding how DNA carries out its biological roles requires knowledge of its
interactions with biological partners. Since DNA is a polyanionic polymer, electrostatic …

Spontaneous assembly of DNA molecules into compact structures is ubiquitous in biological
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …

We perform extensive molecular dynamics simulations of a charged polymer in a good
solvent in the regime where the chain is collapsed. We analyze the dependence of the …

Solutions at high salt concentrations are used to crystallize or segregate charged colloids,
including proteins and polyelectrolytes via a complex mechanism referred to as “salting-out” …

Similarly charged polyelectrolytes are known to attract each other and aggregate into
bundles when the charge density of the polymers exceeds a critical value that depends on …

Charge inversion of DNA is a counterintuitive phenomenon in which the effective charge of
DNA switches its sign from negative to positive in the presence of multivalent counterions …

Acquisition and distribution of metal ions support a number of biological processes. Here we
show that respiratory growth of and iron acquisition by the yeast Saccharomyces cerevisiae …

Negatively charged nanoparticles (NPs) in 1: 1, 1: 2, and 1: 3 electrolyte solutions are
studied in a primitive ion model using molecular dynamics (MD) simulations and classical …

Ion-mediated interaction is important for the properties of polyelectrolytes such as colloids
and nucleic acids. The effective pair interactions between two polyelectrolytes have been …