The role of cullin proteins in gastric cancer
P Chen, GD Yao - Tumor Biology, 2016 - Springer
The cullin proteins are a family of scaffolding proteins that associate with RING proteins and
ubiquitin E3 ligases and mediate substrate–receptor bindings. Thus, cullin proteins regulate …
ubiquitin E3 ligases and mediate substrate–receptor bindings. Thus, cullin proteins regulate …
In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl (CO)(dppb)(bipy)] PF6 [dppb= 1, 4-bis (diphenylphosphine) butane and …
AP Carnizello, MIF Barbosa, M Martins… - Journal of inorganic …, 2016 - Elsevier
This study performed in vitro and in vivo biological assays of the ruthenium (II) compound ct-
[RuCl (CO)(dppb)(bipy)] PF 6 (where, dppb= 1, 4-bis (diphenylphosphine) butane and bipy …
[RuCl (CO)(dppb)(bipy)] PF 6 (where, dppb= 1, 4-bis (diphenylphosphine) butane and bipy …
[HTML][HTML] An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells
ML Gu, YM Wang, XX Zhou, HP Yao… - Oncology …, 2016 - spandidos-publications.com
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm
featured by activated mutations of KIT and PDGFRA. Although overall survival rates have …
featured by activated mutations of KIT and PDGFRA. Although overall survival rates have …
[HTML][HTML] Circadian clock components RORα and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells
S Zhang, J Zhang, Z Deng, H Liu, W Mao, F Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The anticancer small molecule MLN4924, a Nedd8-activating enzyme (NAE) inhibitor,
triggers cell-cycle arrest, apoptosis, and senescence in cancer cells. In this study, we …
triggers cell-cycle arrest, apoptosis, and senescence in cancer cells. In this study, we …
The cytotoxic and pro-apoptotic effects of phenylephrine on corneal stromal cells via a mitochondrion-dependent pathway both in vitro and in vivo
J Zhao, Y Qiu, CL Tian, TJ Fan - Experimental and Toxicologic Pathology, 2016 - Elsevier
Phenylephrine (PHE), a selective α1-adrenergic receptor agonist, is often used as a
decongestant for mydriasis prior to cataract surgery, and its abuse might be cytotoxic to the …
decongestant for mydriasis prior to cataract surgery, and its abuse might be cytotoxic to the …
[HTML][HTML] Stabilising suppressor of cytokine signalling 3 (SOCS3) protein levels to limit neointimal hyperplasia
KMA Munro - 2016 - theses.gla.ac.uk
Suppressor of cytokine signalling 3 (SOCS3) is a potent inhibitor of the mitogenic, migratory
and pro-inflammatory pathways responsible for the development of neointimal hyperplasia …
and pro-inflammatory pathways responsible for the development of neointimal hyperplasia …