The three heteroatoms containing five membered heterocycles such as thiadiazoles have
been extensively studied due to their important pharmacological activities. The thiadiazole …

Thiadiazole derivatives 1–24 were synthesized via a single step reaction and screened for
in vitro β-glucuronidase inhibitory activity. All the synthetic compounds displayed good …

Aims This study was planned to examine the antinociceptive efficacy of agomelatine against
acute mechanical, thermal, and chemical nociceptive stimuli, as well as to determine the …

In the current work, new 1, 3, 4-thiadiazole derivatives were synthesized and investigated for
their antinociceptive effects on nociceptive pathways of nervous system. The effects of these …

This study was planned to investigate possible antinociceptive activity of 1, 5-diaryl-3-[4-
(methylsulfonyl) phenyl]-4, 5-dihydro-1H-pyrazole derivatives (2a-s), based on the analgesia …

The study is devoted to the design and synthesis of new 2, 5-disubstituted 1, 3, 4-
thiadiazoles 3a-k as a promising multi-targeted pharmacological scaffold. Heterocyclization …

Two thiosemicarbazide derivatives 1 and 2, three 2-amino-1, 3, 4-thiadiazole derivatives 3-
5, and three N1-substituted-4-methyl-1, 2, 4-triazole-5-thione derivatives 6-8 were …

YENİ TİYAZOL TÜREVLERİNİN SENTEZİ ve BİYOLOJİK ETKİ ÇALIŞMALARI Ali Ergüç Yüksek
Lisans Tezi Page 1 YENİ TİYAZOL TÜREVLERİNİN SENTEZİ ve BİYOLOJİK ETKİ ÇALIŞMALARI …