Targeting voltage-gated calcium channels in neurological and psychiatric diseases

GW Zamponi - Nature reviews Drug discovery, 2016 - nature.com
Voltage-gated calcium channels are important regulators of brain, heart and muscle
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …

DNA methylation in Huntington's disease: Implications for transgenerational effects

EA Thomas - Neuroscience letters, 2016 - Elsevier
Huntington's disease (HD) is a devastating, neurodegenerative disorder caused by a CAG
repeat mutation in the HTT gene. A growing body of evidence suggests that epigenetic …

[HTML][HTML] WHY NOT POT?: a review of the brain-based risks of cannabis

K MacDonald, K Pappas - Innovations in clinical neuroscience, 2016 - ncbi.nlm.nih.gov
In this review, we provide a historical perspective on marijuana, and survey contemporary
research investigating its potential negative effects on the brain. We discuss the evidence …

Methamphetamine induces the release of endothelin

JW Seo, SM Jones, TA Hostetter, JJ Iliff… - Journal of …, 2016 - Wiley Online Library
Methamphetamine is a potent psychostimulant drug of abuse that increases release and
blocks reuptake of dopamine, producing intense euphoria, factors that may contribute to its …

Structural imaging for addiction medicine: From neurostructure to neuroplasticity

GG Brown, J Jacobus, B McKenna - Progress in brain research, 2016 - Elsevier
Quantitative morphometry and diffusion tensor imaging have provided new insights into
structural brain changes associated with drugs of abuse. In this chapter, we review recent …

[PDF][PDF] Drug abuse and perivascular changes of the brain

P Zogopoulos, S Theocharis, N Kotakidis… - J Clin Exp …, 2016 - researchgate.net
Drug abuse is a major health problem worldwide with severe socioeconomic consequences.
Numerous drugs are widely abused but most common are heroin, cocaine, amphetamines …

Microstructural changes to the brain of mice after methamphetamine exposure as identified with diffusion tensor imaging

BS McKenna, GG Brown, S Archibald… - Psychiatry Research …, 2016 - Elsevier
Methamphetamine (METH) is an addictive psychostimulant inducing neurotoxicity. Human
magnetic resonance imaging and diffusion tensor imaging (DTI) of METH-dependent …

Identifying and addressing the unmet health care needs of drug court clients

KL Dugosh, DS Festinger, JL Lipkin - Journal of substance abuse treatment, 2016 - Elsevier
Drug courts address issues such as employment and housing but largely miss the
opportunity to address important health care issues. The current study examined the …

Tightrope or slackline? The neuroscience of psychoactive substances

P Coulon, A Gorji - Trends in pharmacological sciences, 2016 - cell.com
Novel psychoactive substances flood worldwide markets faster than they can be banned.
Legislators struggle to find a balance between free availability, prescription systems, and …

[PDF][PDF] Αποτίμηση της αντιοξειδωτικής ικανότητας σε χοίρους και κοτόπουλα κρεατοπαραγωγής, μετά από χορήγηση ζωοτροφής, με πολυφαινολικά πρόσθετα από …

ΚΔ Γερασόπουλος - 2016 - ir.lib.uth.gr
Περίληψη To οξειδωτικό στρες αποτελεί μία ανισορροπία μεταξύ της παραγωγής των
ελευθέρων ριζών και την ικανότητα ενός βιολογικού συστήματος να τις εξουδετερώνει και να …