Tissue engineered periodontal products

PM Bartold, S Gronthos, S Ivanovski… - Journal of …, 2016 - Wiley Online Library
Attainment of periodontal regeneration is a significant clinical goal in the management of
advanced periodontal defects arising from periodontitis. Over the past 30 years numerous …

Odontogenic differentiation of human dental pulp stem cells on hydrogel scaffolds derived from decellularized bone extracellular matrix and collagen type I

F Paduano, M Marrelli, LJ White, KM Shakesheff… - PloS one, 2016 - journals.plos.org
Objectives The aim of this study was to evaluate the level of odontogenic differentiation of
dental pulp stem cells (DPSCs) on hydrogel scaffolds derived from bone extracellular matrix …

From restoration to regeneration: periodontal aging and opportunities for therapeutic intervention

L Huang, B Salmon, X Yin, JA Helms - Periodontology 2000, 2016 - Wiley Online Library
With the march of time our bodies start to wear out: eyesight fades, skin loses its elasticity,
teeth and bones become more brittle and injuries heal more slowly. These universal …

Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment

Y An, W Liu, P Xue, Y Zhang… - Journal of Clinical …, 2016 - Wiley Online Library
Objective Autophagy, which provides a mechanism for turnover cellular organelles and
proteins through a lysosome‐dependent degradation pathway, has been related to the …

High glucose concentrations suppress the proliferation of human periodontal ligament stem cells and their differentiation into osteoblasts

H Kato, Y Taguchi, K Tominaga… - Journal of …, 2016 - Wiley Online Library
Background: Diabetes mellitus (DM) is a major risk factor for periodontal disease and affects
various cellular functions. Periodontal ligament stem cells (PDLSCs) play an important role …

CD8+ T cells mediate the regenerative PTH effect in hPDL cells via Wnt10b signaling

M Wolf, S Lossdörfer, J Marciniak, P Römer… - Innate …, 2016 - journals.sagepub.com
It was the aim of the present investigation to examine whether the stimulating effect of
parathyroid hormone (PTH) on human periodontal ligament (hPDL) cell proliferation and …

[PDF][PDF] The prospect of chitosan on the osteogenesis of periodontal ligament stem cells

Y Soeroso, EW Bachtiar, MB Boy, B Sulijaya… - Journal of International …, 2016 - academia.edu
Biomaterial innovation is needed for bone substitute which can help the osteogenesis
process on periodontal tissue regeneration. This study is an experimental in-vitro study of …

[HTML][HTML] The effect of 1α, 25 (OH) 2D3 on osteogenic differentiation of stem cells from dental pulp of exfoliated deciduous teeth

F Mojarad, I Amiri, R Rafatjou, A Janeshin… - Journal of …, 2016 - ncbi.nlm.nih.gov
Purpose: The aim of this study was to investigate the effect of 1α, 25-dihydroxyvitamin D3 on
osteogenic differentiation (alkaline phosphatase activity and alizarin red staining) of stem …

[PDF][PDF] Activation of TLR3 enhance stemness and immunomodulatory properties of periodontal ligament stem cells (PDLSCs)

N Klincumhom, D Chaikeawkaew… - Interface Oral Health …, 2016 - library.oapen.org
Periodontal ligament stem cells (PDLSCs) have been served as a cell reservoir for tissue
regeneration during adulthood. For clinical applications, the challenging steps are to …

Neuropilin controls endothelial differentiation by mesenchymal stem cells from the periodontal ligament

BR Amorim, KG Silvério, MZ Casati… - Journal of …, 2016 - Wiley Online Library
Background: Periodontal ligament (PDL) has been reported to be a source of mesenchymal
stem cells (MSCs). New vascular networks from undifferentiated cells are essential for …