Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis
Background Anti-citrullinated protein antibodies (ACPAs) are the hallmark of rheumatoid
arthritis (RA). Protein citrullination is believed to drive autoantigen selection in RA …
arthritis (RA). Protein citrullination is believed to drive autoantigen selection in RA …
MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF
DM Boeters, WP Nieuwenhuis, MK Verheul… - Arthritis research & …, 2016 - Springer
Background In rheumatoid arthritis (RA) bone marrow edema (BME, osteitis) and anti-
citrullinated protein antibodies (ACPA) are associated with radiographic progression. ACPA …
citrullinated protein antibodies (ACPA) are associated with radiographic progression. ACPA …
Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome‐Wide Association Study
Objective Rheumatoid factor (RF) is a well‐established diagnostic and prognostic biomarker
in rheumatoid arthritis (RA). However,∼ 20% of RA patients are negative for this anti‐IgG …
in rheumatoid arthritis (RA). However,∼ 20% of RA patients are negative for this anti‐IgG …
A Transmembrane Polymorphism of Fcγ Receptor IIb Is Associated with Kidney Deficiency Syndrome in Rheumatoid Arthritis
N Mo, R Lai, S Luo, J Xie, X Wang, L Liu… - Evidence‐Based …, 2016 - Wiley Online Library
Objective. The purpose is to investigate the role of kidney deficiency and the association
between kidney deficiency and a polymorphism FcγRIIb 695T> C coding for …
between kidney deficiency and a polymorphism FcγRIIb 695T> C coding for …
Rôle de polymorphismes nucléotidiques dans les gènes de l'interleukine-4 et son récepteur et du corécepteur cd40, et des allèles hla-dr, dans la progression de la …
G Sauvageau - 2016 - search.proquest.com
Jusqu'à 1% de la population canadienne est affectée par la polyarthrite rhumatoïde, une
maladie causant de la douleur, un handicap progressif, et des manifestations systémiques …
maladie causant de la douleur, un handicap progressif, et des manifestations systémiques …
生物学的製剤使用下に人工膝関節全置換術を施行した関節リウマチ患者の疾患活動性と関節破壊進行の関連性
武部健， 丸野文雅， 上藤敦郎， 立石耕司， 寺島康浩… - 日本関節病学会 …, 2016 - jstage.jst.go.jp
Objective: The aim of the present study was to investigate the association between disease
activity of rheumatoid arthritis (RA) and radiographic progression in patients using biological …
activity of rheumatoid arthritis (RA) and radiographic progression in patients using biological …