Building nanostructures with drugs
W Ma, AG Cheetham, H Cui - Nano today, 2016 - Elsevier
The convergence of nanoscience and drug delivery has prompted the formation of the field
of nanomedicine, one that exploits the novel physicochemical and biological properties of …
of nanomedicine, one that exploits the novel physicochemical and biological properties of …
Anticancer nanoparticulate polymer‐drug conjugate
We review recent progress in polymer‐drug conjugate for cancer nanomedicine. Polymer‐
drug conjugates, including the nanoparticle prepared from these conjugates, are designed …
drug conjugates, including the nanoparticle prepared from these conjugates, are designed …
Doxorubicin-loaded biodegradable self-assembly zein nanoparticle and its anti-cancer effect: Preparation, in vitro evaluation, and cellular uptake
F Dong, X Dong, L Zhou, H Xiao, PY Ho… - Colloids and Surfaces B …, 2016 - Elsevier
Cancer is one top leading cause of the deaths worldwide. Various anticancer drugs, which
can effectively kill cancer cells, have been developed in the last decade. However, the …
can effectively kill cancer cells, have been developed in the last decade. However, the …
A small molecule nanodrug consisting of amphiphilic targeting ligand–chemotherapy drug conjugate for targeted cancer therapy
Targeted drug delivery is a broadly applicable approach for cancer therapy. However, the
nanocarrier-based targeted delivery system suffers from batch-to-batch variation, quality …
nanocarrier-based targeted delivery system suffers from batch-to-batch variation, quality …
Supramolecular vesicles based on complex of trp-modified pillar [5] arene and galactose derivative for synergistic and targeted drug delivery
Failure of cancer treatment is mainly caused by adverse side effects to normal cells and
multidrug resistance (MDR) of cancer cells induced by chemotherapy. 1, 2 Targeting and …
multidrug resistance (MDR) of cancer cells induced by chemotherapy. 1, 2 Targeting and …
Traceable nanoparticle delivery of small interfering RNA and retinoic acid with temporally release ability to control neural stem cell differentiation for Alzheimer's …
R Zhang, Y Li, B Hu, Z Lu, J Zhang… - Advanced …, 2016 - Wiley Online Library
DOI: 10.1002/adma. 201600554 application of NSCs would be based on controlled
differentiation of NSCs to neurons and long-term monitoring in real time. For the aspect of …
differentiation of NSCs to neurons and long-term monitoring in real time. For the aspect of …
Facile construction of pH-and redox-responsive micelles from a biodegradable poly (β-hydroxyl amine) for drug delivery
D Li, Y Bu, L Zhang, X Wang, Y Yang… - …, 2016 - ACS Publications
Here we demonstrate a type of pH and reduction dual-sensitive biodegradable micelles,
which were self-assembled by a cationic polymer in an aqueous solution. Due to tumor cells …
which were self-assembled by a cationic polymer in an aqueous solution. Due to tumor cells …
Self-assembled targeted nanoparticles based on transferrin-modified eight-arm-polyethylene glycol–dihydroartemisinin conjugate
K Liu, L Dai, C Li, J Liu, L Wang, J Lei - Scientific Reports, 2016 - nature.com
Poor delivery of insoluble anticancer drugs has so far precluded their clinical application. In
this study, an efficient tumor targeted-nanoparticle delivery system, transferrin-eight-arm …
this study, an efficient tumor targeted-nanoparticle delivery system, transferrin-eight-arm …
Self-delivery of a peptide-based prodrug for tumor-targeting therapy
A novel self-delivered prodrug system was fabricated for tumor-targeting therapy. In this
nanosystem, the Arg-Gly-Asp-Ser (RGDS) tetrapeptide was used to improve the therapeutic …
nanosystem, the Arg-Gly-Asp-Ser (RGDS) tetrapeptide was used to improve the therapeutic …
One-step “click chemistry”-synthesized cross-linked prodrug nanogel for highly selective intracellular drug delivery and upregulated antitumor efficacy
Polymeric prodrugs formed by the conjugation of drugs onto polymers have shown great
promise in cancer therapy because of the enhancement of water solubility, elimination of …
promise in cancer therapy because of the enhancement of water solubility, elimination of …