Molecular mechanisms underlying psychological stress and cancer

K Jin Shin, Y Jin Lee, Y Ryoul Yang… - Current …, 2016 - ingentaconnect.com
Psychological stress is an emotion experienced when people are under mental pressure or
encounter unexpected problems. Extreme or repetitive stress increases the risk of …

[HTML][HTML] Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway

C Zhou, X Chen, W Zeng, C Peng, G Huang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Both preclinical and epidemiology studies associate β-adrenoceptors-blockers (β-blockers)
with activity against melanoma. However, the underlying mechanism is still unclear …

Selective β2‐AR blockage suppresses colorectal cancer growth through regulation of EGFR‐Akt/ERK1/2 signaling, G1‐phase arrest, and apoptosis

CC Chin, JM Li, KF Lee, YC Huang… - Journal of Cellular …, 2016 - Wiley Online Library
The stress‐upregulated catecholamines‐activated β1‐and β2‐adrenergic receptors (β1/2‐
ARs) have been shown to accelerate the progression of cancers such as colorectal cancer …

The potential anticancer effect of beta-blockers and the genetic variations involved in the interindividual difference

RH He, YJ He, YJ Tang, HH Zhou, HL McLeod… - …, 2016 - Taylor & Francis
β-ARs are extensively spread in different tissues of our body, which could be activated by
neurotransmitters norepinephrine and epinephrine to mediate physiological function and …

β2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma (PDAC) progression through facilitating PCBP2-dependent c-myc expression

C Wan, C Gong, H Zhang, L Hua, X Li, X Chen, Y Chen… - Cancer letters, 2016 - Elsevier
The β2-adrenergic receptor (β2-AR) plays a crucial role in pancreatic ductal
adenocarcinoma (PDAC) progression. In this report, we identified poly (rC)-binding protein 2 …

Metastasis risk reduction related with beta-blocker treatment in Mexican women with breast cancer

E Parada-Huerta, JA Ponce-Medrano… - Asian Pacific Journal …, 2016 - journal.waocp.org
Background: Breast Cancer (BCa) is the most common malignant tumour in Mexican
women. In BCa, several studies have linked β2-adrenergic receptor activation with …

[PDF][PDF] Journal of Anesthesia & Clinical Research

K Laudanski, R Wei, L Korley - 2016 - researchgate.net
Alongside the known direct, short-term effects of anesthesia in general, there is emerging
evidence of an immunomodulatory effect with specific anesthetics that may decrease …

[PDF][PDF] Parameter der Tumorprogression von humanen Pankreaskarzinomzellen unter Katecholaminexposition in vitro und therapierbare Effekte von chronischem …

S Speerforck - 2016 - epub.ub.uni-greifswald.de
Das Pankreaskarzinom ist die zehnthäufigste (Männer) bzw. neunthäufigste (Frauen)
Tumorerkrankung in Deutschland. Aufgrund der häufig fatalen Prognose ist es gleichzeitig …

Essential roles of CD27/CD70 co-stimulation and β2-adrenergic receptor signaling in suppressing GVHD

ND Leigh - 2016 - search.proquest.com
Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment
for hematologic disorders. However, graft-versus-host disease (GVHD) may develop when …

Understanding the Impact of Adrenergic Stress on the Therapeutic Response of Murine Cancer Models

JWL Eng - 2016 - search.proquest.com
Laboratory mice are indispensable tools used in cancer research to model and study
multiple aspects of tumor biology. In particular, the development of new therapies for the …