We update complementary learning systems (CLS) theory, which holds that intelligent
agents must possess two learning systems, instantiated in mammalians in neocortex and …

The storage of information in the mammalian nervous systems is dependent on a delicate
balance between change and stability of neuronal networks. The induction and …

The meaning we derive from our experiences is not a simple static extraction of the elements
but is largely based on the order in which those elements occur. Models propose that …

Cell assembly sequences during learning are “replayed” during hippocampal ripples and
contribute to the consolidation of episodic memories. However, neuronal sequences may …

How does an animal know where it is when it stops moving? Hippocampal place cells fire at
discrete locations as subjects traverse space, thereby providing an explicit neural code for …

Fast internally generated sequences of neural representations are suggested to support
learning and online planning. However, these sequences have only been studied in the …

The hippocampus is critical to the memory for sequences of events, a defining feature of
episodic memory. However, the fundamental neuronal mechanisms underlying this capacity …

The dentate gyrus (DG) is important for encoding contextual memories, but little is known
about how a population of DG neurons comes to encode and support a particular memory …

Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer's disease (AD), but the
mechanism by which it causes cognitive decline is unclear. In knockin (KI) mice, human …

Colloquially, episodic memory is described as “the memory of personally experienced
events”. Even though episodic memory has been studied in psychology and neuroscience …